Dissemination of Acinetobacter baumannii clones with OXA-23 Carbapenemase in Colombian hospitals

Maria Virginia Villegas; Juan Nicolas Kattan; Adriana Correa; Karen Lolans; Ana Maria Guzman; Neil Woodford; David Livermore; John P Quinn

doi:10.1128/AAC.00226-07

Dissemination of Acinetobacter baumannii clones with OXA-23 Carbapenemase in Colombian hospitals

Maria Virginia Villegas, Juan Nicolas Kattan, Adriana Correa, Karen Lolans, Ana Maria Guzman, Neil Woodford, David Livermore, John P Quinn

Research output: Contribution to journal › Article › peer-review

67 Citations (Scopus)

Abstract

During 2005, 66 carbapenem-resistant isolates of Acinetobacter baumannii were collected from seven tertiary-care hospitals participating in a nationwide surveillance network in Colombia. The isolates were multidrug resistant and produced the carbapenemases OXA-23 and OXA-51. Forty-five belonged to four clones while 21 were unique pulsotypes. One clone was present in two hospitals within one city, while another had spread between two hospitals in different cities. Blood, secretions, and abdominal fluids were the most frequent sites of isolation. This is the first description of widespread dissemination of OXA-23 in South America.

Original language	English
Pages (from-to)	2001-2004
Number of pages	4
Journal	Antimicrobial Agents and Chemotherapy
Volume	51
Issue number	6
DOIs	https://doi.org/10.1128/AAC.00226-07
Publication status	Published - Jun 2007

Keywords

Acinetobacter Infections
Acinetobacter baumannii
Anti-Bacterial Agents
Bacterial Proteins
Carbapenems
Colombia
Hospitals
Humans
Microbial Sensitivity Tests
Polymerase Chain Reaction
Population Surveillance
beta-Lactam Resistance
beta-Lactamases

Access to Document

10.1128/AAC.00226-07

Cite this

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title = "Dissemination of Acinetobacter baumannii clones with OXA-23 Carbapenemase in Colombian hospitals",

abstract = "During 2005, 66 carbapenem-resistant isolates of Acinetobacter baumannii were collected from seven tertiary-care hospitals participating in a nationwide surveillance network in Colombia. The isolates were multidrug resistant and produced the carbapenemases OXA-23 and OXA-51. Forty-five belonged to four clones while 21 were unique pulsotypes. One clone was present in two hospitals within one city, while another had spread between two hospitals in different cities. Blood, secretions, and abdominal fluids were the most frequent sites of isolation. This is the first description of widespread dissemination of OXA-23 in South America.",

keywords = "Acinetobacter Infections, Acinetobacter baumannii, Anti-Bacterial Agents, Bacterial Proteins, Carbapenems, Colombia, Hospitals, Humans, Microbial Sensitivity Tests, Polymerase Chain Reaction, Population Surveillance, beta-Lactam Resistance, beta-Lactamases",

author = "Villegas, {Maria Virginia} and Kattan, {Juan Nicolas} and Adriana Correa and Karen Lolans and Guzman, {Ana Maria} and Neil Woodford and David Livermore and Quinn, {John P}",

year = "2007",

month = jun,

doi = "10.1128/AAC.00226-07",

language = "English",

volume = "51",

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journal = "Antimicrobial Agents and Chemotherapy",

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publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Dissemination of Acinetobacter baumannii clones with OXA-23 Carbapenemase in Colombian hospitals

AU - Villegas, Maria Virginia

AU - Kattan, Juan Nicolas

AU - Correa, Adriana

AU - Lolans, Karen

AU - Guzman, Ana Maria

AU - Woodford, Neil

AU - Livermore, David

AU - Quinn, John P

PY - 2007/6

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AB - During 2005, 66 carbapenem-resistant isolates of Acinetobacter baumannii were collected from seven tertiary-care hospitals participating in a nationwide surveillance network in Colombia. The isolates were multidrug resistant and produced the carbapenemases OXA-23 and OXA-51. Forty-five belonged to four clones while 21 were unique pulsotypes. One clone was present in two hospitals within one city, while another had spread between two hospitals in different cities. Blood, secretions, and abdominal fluids were the most frequent sites of isolation. This is the first description of widespread dissemination of OXA-23 in South America.

KW - Acinetobacter Infections

KW - Acinetobacter baumannii

KW - Anti-Bacterial Agents

KW - Bacterial Proteins

KW - Carbapenems

KW - Colombia

KW - Hospitals

KW - Humans

KW - Microbial Sensitivity Tests

KW - Polymerase Chain Reaction

KW - Population Surveillance

KW - beta-Lactam Resistance

KW - beta-Lactamases

U2 - 10.1128/AAC.00226-07

DO - 10.1128/AAC.00226-07

M3 - Article

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VL - 51

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JO - Antimicrobial Agents and Chemotherapy

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SN - 0066-4804

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