Dissemination of Acinetobacter baumannii clones with OXA-23 Carbapenemase in Colombian hospitals

Maria Virginia Villegas, Juan Nicolas Kattan, Adriana Correa, Karen Lolans, Ana Maria Guzman, Neil Woodford, David Livermore, John P Quinn

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During 2005, 66 carbapenem-resistant isolates of Acinetobacter baumannii were collected from seven tertiary-care hospitals participating in a nationwide surveillance network in Colombia. The isolates were multidrug resistant and produced the carbapenemases OXA-23 and OXA-51. Forty-five belonged to four clones while 21 were unique pulsotypes. One clone was present in two hospitals within one city, while another had spread between two hospitals in different cities. Blood, secretions, and abdominal fluids were the most frequent sites of isolation. This is the first description of widespread dissemination of OXA-23 in South America.
Original languageEnglish
Pages (from-to)2001-2004
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Issue number6
Publication statusPublished - Jun 2007


  • Acinetobacter Infections
  • Acinetobacter baumannii
  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Carbapenems
  • Colombia
  • Hospitals
  • Humans
  • Microbial Sensitivity Tests
  • Polymerase Chain Reaction
  • Population Surveillance
  • beta-Lactam Resistance
  • beta-Lactamases

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