Dissemination of pCT-like IncK plasmids harboring CTX-M-14 extended-spectrum β-lactamase among clinical Escherichia coli isolates in the United Kingdom

Hiran Dhanji, Parmina Khan, Jennifer L. Cottell, Laura J. V. Piddock, Jiancheng Zhang, David M. Livermore, Neil Woodford

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IncK plasmids encoding CTX-M-14 extended-spectrum β-lactamase (ESBL) and highly related to plasmid pCT were detected in 13 of 67 (19%) human clinical isolates of Escherichia coli with a group 9 CTX-M-type ESBL from the United Kingdom and in 2 quality assurance isolates. None of these E. coli strains was related to the cattle strain from which pCT was originally characterized.
Original languageEnglish
Pages (from-to)3376-3377
Number of pages2
JournalAntimicrobial Agents and Chemotherapy
Issue number6
Publication statusPublished - Jun 2012


  • Escherichia coli
  • Great Britain
  • Phylogeny
  • Plasmids
  • beta-Lactamases

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