Dissemination of pCT-like IncK plasmids harboring CTX-M-14 extended-spectrum β-lactamase among clinical Escherichia coli isolates in the United Kingdom

Hiran Dhanji; Parmina Khan; Jennifer L. Cottell; Laura J. V. Piddock; Jiancheng Zhang; David M. Livermore; Neil Woodford

doi:10.1128/AAC.00313-12

Dissemination of pCT-like IncK plasmids harboring CTX-M-14 extended-spectrum β-lactamase among clinical Escherichia coli isolates in the United Kingdom

Hiran Dhanji
, Parmina Khan
, Jennifer L. Cottell
, Laura J. V. Piddock
, Jiancheng Zhang
, David M. Livermore
, Neil Woodford

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

IncK plasmids encoding CTX-M-14 extended-spectrum β-lactamase (ESBL) and highly related to plasmid pCT were detected in 13 of 67 (19%) human clinical isolates of Escherichia coli with a group 9 CTX-M-type ESBL from the United Kingdom and in 2 quality assurance isolates. None of these E. coli strains was related to the cattle strain from which pCT was originally characterized.

Original language	English
Pages (from-to)	3376-3377
Number of pages	2
Journal	Antimicrobial Agents and Chemotherapy
Volume	56
Issue number	6
DOIs	https://doi.org/10.1128/AAC.00313-12
Publication status	Published - Jun 2012

Keywords

Escherichia coli
Great Britain
Phylogeny
Plasmids
beta-Lactamases

Access to Document

10.1128/AAC.00313-12

Cite this

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title = "Dissemination of pCT-like IncK plasmids harboring CTX-M-14 extended-spectrum β-lactamase among clinical Escherichia coli isolates in the United Kingdom",

abstract = "IncK plasmids encoding CTX-M-14 extended-spectrum β-lactamase (ESBL) and highly related to plasmid pCT were detected in 13 of 67 (19\%) human clinical isolates of Escherichia coli with a group 9 CTX-M-type ESBL from the United Kingdom and in 2 quality assurance isolates. None of these E. coli strains was related to the cattle strain from which pCT was originally characterized.",

keywords = "Escherichia coli, Great Britain, Phylogeny, Plasmids, beta-Lactamases",

author = "Hiran Dhanji and Parmina Khan and Cottell, \{Jennifer L.\} and Piddock, \{Laura J. V.\} and Jiancheng Zhang and Livermore, \{David M.\} and Neil Woodford",

year = "2012",

month = jun,

doi = "10.1128/AAC.00313-12",

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journal = "Antimicrobial Agents and Chemotherapy",

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AU - Dhanji, Hiran

AU - Khan, Parmina

AU - Cottell, Jennifer L.

AU - Piddock, Laura J. V.

AU - Zhang, Jiancheng

AU - Livermore, David M.

AU - Woodford, Neil

PY - 2012/6

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N2 - IncK plasmids encoding CTX-M-14 extended-spectrum β-lactamase (ESBL) and highly related to plasmid pCT were detected in 13 of 67 (19%) human clinical isolates of Escherichia coli with a group 9 CTX-M-type ESBL from the United Kingdom and in 2 quality assurance isolates. None of these E. coli strains was related to the cattle strain from which pCT was originally characterized.

AB - IncK plasmids encoding CTX-M-14 extended-spectrum β-lactamase (ESBL) and highly related to plasmid pCT were detected in 13 of 67 (19%) human clinical isolates of Escherichia coli with a group 9 CTX-M-type ESBL from the United Kingdom and in 2 quality assurance isolates. None of these E. coli strains was related to the cattle strain from which pCT was originally characterized.

KW - Escherichia coli

KW - Great Britain

KW - Phylogeny

KW - Plasmids

KW - beta-Lactamases

U2 - 10.1128/AAC.00313-12

DO - 10.1128/AAC.00313-12

M3 - Article

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SN - 0066-4804

VL - 56

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EP - 3377

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

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