Abstract
Most Crohn's disease (CD) patients show seroreactivity against Mycobacterium avium paratuberculosis (MAP), suggesting a pathogenic role for this organism. Our aim was to seek amino acid similarities between MAP and intestinal proteins that, through molecular mimicry, could serve as targets for cross-reactive immunity in CD.
| Original language | English |
|---|---|
| Pages (from-to) | 85-96 |
| Number of pages | 12 |
| Journal | Gastroenterology |
| Volume | 131 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jul 2006 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Antibody Affinity
- Autoantigens
- Crohn Disease
- Enzyme-Linked Immunosorbent Assay
- Female
- Glutathione Peroxidase
- Humans
- Male
- Middle Aged
- Mycobacterium avium subsp. paratuberculosis
- Paratuberculosis
- Prognosis
- Severity of Illness Index
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