Early molecular events in PAMP-triggered immunity

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In plant innate immunity, the first line of microbial recognition leading to active defence responses relies on the perception of pathogen-associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs). This recognition leads to PAMP-triggered immunity (PTI). Despite the numerous PAMPs recognised by plants, only a handful of PRRs are characterised. For most, they correspond to transmembrane proteins with a ligand-binding ectodomain. PRRs interact with additional transmembrane proteins that act as signalling adapters or amplifiers to achieve full functionality. The crucial role of PRRs in anti-microbial immunity is demonstrated by the direct targeting of PRRs and their associated proteins by pathogenic virulence effectors.
Original languageEnglish
Pages (from-to)414-20
Number of pages7
JournalCurrent Opinion in Plant Biology
Issue number4
Publication statusPublished - Aug 2009


  • Host-Pathogen Interactions
  • Immunity, Innate
  • Membrane Proteins
  • Models, Biological
  • Plant Diseases
  • Plant Proteins
  • Plants
  • Protein Binding
  • Receptors, Pattern Recognition
  • Signal Transduction

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