Effect of adenosine on P2X7 receptor-mediated Ca2+ signalling in human Muller cells and retinal neurons

Julie Sanderson, D.J. Colison, Julie A Eldred, George Duncan, David C Broadway

Research output: Contribution to journalArticlepeer-review


The P2X7 ATP receptor is proposed to play a role in apoptosis. Functional expression of this receptor in human retinal cells in culture was investigated using the P2X7 agonist BzATP. Adenosine is a proposed neuromodulator in the retina. The effect of adenosine on BzATP-induced Ca2+ signalling was also investigated.
Original languageEnglish
Pages (from-to)5204
Number of pages1
JournalInvestigative Ophthalmology and Visual Science
Publication statusPublished - 2003

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