Effect of adenosine on P2X7 receptor-mediated Ca2+ signalling in human Muller cells and retinal neurons

Julie Sanderson; D.J. Colison; Julie A Eldred; George Duncan; David C Broadway

Effect of adenosine on P2X7 receptor-mediated Ca2+ signalling in human Muller cells and retinal neurons

Julie Sanderson
, D.J. Colison
, Julie A Eldred
, George Duncan
, David C Broadway

Research output: Contribution to journal › Article › peer-review

Abstract

The P2X7 ATP receptor is proposed to play a role in apoptosis. Functional expression of this receptor in human retinal cells in culture was investigated using the P2X7 agonist BzATP. Adenosine is a proposed neuromodulator in the retina. The effect of adenosine on BzATP-induced Ca2+ signalling was also investigated.

Original language	English
Pages (from-to)	5204
Number of pages	1
Journal	Investigative Ophthalmology and Visual Science
Volume	44
Publication status	Published - 2003

Access to Document

https://iovs.arvojournals.org/article.aspx?articleid=2417004

Cite this

@article{a139a00324dd47ff96ffde0047dc99be,

title = "Effect of adenosine on P2X7 receptor-mediated Ca2+ signalling in human Muller cells and retinal neurons",

abstract = "The P2X7 ATP receptor is proposed to play a role in apoptosis. Functional expression of this receptor in human retinal cells in culture was investigated using the P2X7 agonist BzATP. Adenosine is a proposed neuromodulator in the retina. The effect of adenosine on BzATP-induced Ca2+ signalling was also investigated.",

author = "Julie Sanderson and D.J. Colison and Eldred, \{Julie A\} and George Duncan and Broadway, \{David C\}",

year = "2003",

language = "English",

volume = "44",

pages = "5204",

journal = "Investigative Ophthalmology and Visual Science",

issn = "1552-5783",

publisher = "Association for Research in Vision and Ophthalmology Inc.",

}

TY - JOUR

T1 - Effect of adenosine on P2X7 receptor-mediated Ca2+ signalling in human Muller cells and retinal neurons

AU - Sanderson, Julie

AU - Colison, D.J.

AU - Eldred, Julie A

AU - Duncan, George

AU - Broadway, David C

PY - 2003

Y1 - 2003

N2 - The P2X7 ATP receptor is proposed to play a role in apoptosis. Functional expression of this receptor in human retinal cells in culture was investigated using the P2X7 agonist BzATP. Adenosine is a proposed neuromodulator in the retina. The effect of adenosine on BzATP-induced Ca2+ signalling was also investigated.

AB - The P2X7 ATP receptor is proposed to play a role in apoptosis. Functional expression of this receptor in human retinal cells in culture was investigated using the P2X7 agonist BzATP. Adenosine is a proposed neuromodulator in the retina. The effect of adenosine on BzATP-induced Ca2+ signalling was also investigated.

M3 - Article

SN - 1552-5783

VL - 44

SP - 5204

JO - Investigative Ophthalmology and Visual Science

JF - Investigative Ophthalmology and Visual Science

ER -