Abstract
The effect of calcium intake on the calcium absorption efficiency from 100 mL cow milk was measured in lactating Gambian mothers habituated to a low-calcium diet [mean intake 7.08 mmol (283 mg)/d], and compared with UK lactating mothers consuming high-calcium diets [mean intake 29.2 mmol (1168 mg)/d] by using a double stable-isotope technique (oral 44Ca and intravenous 42Ca). In a double-blind trial starting 9 d postpartum, Gambian mothers were given a calcium supplement [17.85 mmol (714 mg)/d] or placebo for 12 mo. At 3 and 12 mo postpartum, mean (+/- SEM) calcium absorption from isotopically enriched milk was 52.3 +/- 3.1% (n = 25) and 47.2 +/- 4.8% (n = 24) in the unsupplemented Gambian mothers and 48.8 +/- 2.8% (n = 28) and 42.9 +/- 3.7% (n = 24) in the supplemented mothers, respectively. There was no effect of supplementation or stage of lactation on the efficiency of calcium absorption. At 3 mo postpartum the UK mothers absorbed 32.2 +/- 3.8% of the isotopically enriched calcium added to milk, which was significantly less than that of the Gambian mothers (P
Original language | English |
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Pages (from-to) | 1188-1192 |
Number of pages | 5 |
Journal | American Journal of Clinical Nutrition |
Volume | 62 |
Issue number | 6 |
DOIs | |
Publication status | Published - Dec 1995 |
Keywords
- Absorption
- Administration, Oral
- Adult
- Animals
- Calcium
- Calcium Isotopes
- Calcium, Dietary
- Dose-Response Relationship, Drug
- Double-Blind Method
- Female
- Food, Fortified
- Gambia
- Great Britain
- Humans
- Injections, Intravenous
- Lactation
- Mass Spectrometry
- Milk