Effect of communicating DNA based risk assessments for Crohn's disease on smoking cessation: randomised controlled trial

Gareth J Hollands; Sophia C L Whitwell; Richard A Parker; Natalie J Prescott; Alastair Forbes; Jeremy Sanderson; Christopher G Mathew; Cathryn M Lewis; Sally Watts; Stephen Sutton; David Armstrong; Ann Louise Kinmonth; A Toby Prevost; Theresa M Marteau

doi:10.1136/bmj.e4708

Effect of communicating DNA based risk assessments for Crohn's disease on smoking cessation: randomised controlled trial

Gareth J Hollands, Sophia C L Whitwell, Richard A Parker, Natalie J Prescott, Alastair Forbes, Jeremy Sanderson, Christopher G Mathew, Cathryn M Lewis, Sally Watts, Stephen Sutton, David Armstrong, Ann Louise Kinmonth, A Toby Prevost, Theresa M Marteau

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

To test the hypothesis that communicating risk of developing Crohn's disease based on genotype and that stopping smoking can reduce this risk, motivates behaviour change among smokers at familial risk.

Original language	English
Pages (from-to)	e4708
Journal	BMJ-British Medical Journal
Volume	345
DOIs	https://doi.org/10.1136/bmj.e4708
Publication status	Published - 2012

Keywords

Adult
Attitude to Health
Crohn Disease
DNA Mutational Analysis
Family
Female
Genetic Predisposition to Disease
Genetic Testing
Great Britain
Humans
Male
Middle Aged
Motivation
Nod2 Signaling Adaptor Protein
Outcome Assessment (Health Care)
Risk Assessment
Smoking
Smoking Cessation

Access to Document

10.1136/bmj.e4708

Cite this

Hollands, G. J., Whitwell, S. C. L., Parker, R. A., Prescott, N. J., Forbes, A., Sanderson, J., Mathew, C. G., Lewis, C. M., Watts, S., Sutton, S., Armstrong, D., Kinmonth, A. L., Prevost, A. T., & Marteau, T. M. (2012). Effect of communicating DNA based risk assessments for Crohn's disease on smoking cessation: randomised controlled trial. BMJ-British Medical Journal, 345, e4708. https://doi.org/10.1136/bmj.e4708

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abstract = "To test the hypothesis that communicating risk of developing Crohn's disease based on genotype and that stopping smoking can reduce this risk, motivates behaviour change among smokers at familial risk.",

keywords = "Adult, Attitude to Health, Crohn Disease, DNA Mutational Analysis, Family, Female, Genetic Predisposition to Disease, Genetic Testing, Great Britain, Humans, Male, Middle Aged, Motivation, Nod2 Signaling Adaptor Protein, Outcome Assessment (Health Care), Risk Assessment, Smoking, Smoking Cessation",

author = "Hollands, {Gareth J} and Whitwell, {Sophia C L} and Parker, {Richard A} and Prescott, {Natalie J} and Alastair Forbes and Jeremy Sanderson and Mathew, {Christopher G} and Lewis, {Cathryn M} and Sally Watts and Stephen Sutton and David Armstrong and Kinmonth, {Ann Louise} and Prevost, {A Toby} and Marteau, {Theresa M}",

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Hollands, GJ, Whitwell, SCL, Parker, RA, Prescott, NJ, Forbes, A, Sanderson, J, Mathew, CG, Lewis, CM, Watts, S, Sutton, S, Armstrong, D, Kinmonth, AL, Prevost, AT & Marteau, TM 2012, 'Effect of communicating DNA based risk assessments for Crohn's disease on smoking cessation: randomised controlled trial', BMJ-British Medical Journal, vol. 345, pp. e4708. https://doi.org/10.1136/bmj.e4708

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T1 - Effect of communicating DNA based risk assessments for Crohn's disease on smoking cessation

T2 - randomised controlled trial

AU - Hollands, Gareth J

AU - Whitwell, Sophia C L

AU - Parker, Richard A

AU - Prescott, Natalie J

AU - Forbes, Alastair

AU - Sanderson, Jeremy

AU - Mathew, Christopher G

AU - Lewis, Cathryn M

AU - Watts, Sally

AU - Sutton, Stephen

AU - Armstrong, David

AU - Kinmonth, Ann Louise

AU - Prevost, A Toby

AU - Marteau, Theresa M

PY - 2012

Y1 - 2012

N2 - To test the hypothesis that communicating risk of developing Crohn's disease based on genotype and that stopping smoking can reduce this risk, motivates behaviour change among smokers at familial risk.

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KW - Adult

KW - Attitude to Health

KW - Crohn Disease

KW - DNA Mutational Analysis

KW - Family

KW - Female

KW - Genetic Predisposition to Disease

KW - Genetic Testing

KW - Great Britain

KW - Humans

KW - Male

KW - Middle Aged

KW - Motivation

KW - Nod2 Signaling Adaptor Protein

KW - Outcome Assessment (Health Care)

KW - Risk Assessment

KW - Smoking

KW - Smoking Cessation

U2 - 10.1136/bmj.e4708

DO - 10.1136/bmj.e4708

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JO - BMJ-British Medical Journal

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