Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model

Karsten Lenk, Sandra Palus, Robert Schur, Rakesh Datta, Jesse Dong, Michael D. Culler, Stefan Anker, Jochen Springer, Gerhard Schuler, Volker Adams

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43 Citations (Scopus)


In an animal model of CHF, the expression of myostatin is significantly reduced in the skeletal muscle after application of ghrelin and most concentrations of its analogues BIM-28125 and BIM-28131 possibly due to anti-inflammatory effects.
Original languageEnglish
Pages (from-to)63-69
Number of pages7
JournalJournal of Cachexia, Sarcopenia and Muscle
Issue number1
Publication statusPublished - 2013

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