Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model

Karsten Lenk; Sandra Palus; Robert Schur; Rakesh Datta; Jesse Dong; Michael D. Culler; Stefan Anker; Jochen Springer; Gerhard Schuler; Volker Adams

doi:10.1007/s13539-012-0085-3

Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model

Karsten Lenk, Sandra Palus, Robert Schur, Rakesh Datta, Jesse Dong, Michael D. Culler, Stefan Anker, Jochen Springer, Gerhard Schuler, Volker Adams

Research output: Contribution to journal › Article › peer-review

45 Citations (Scopus)

Abstract

In an animal model of CHF, the expression of myostatin is significantly reduced in the skeletal muscle after application of ghrelin and most concentrations of its analogues BIM-28125 and BIM-28131 possibly due to anti-inflammatory effects.

Original language	English
Pages (from-to)	63-69
Number of pages	7
Journal	Journal of Cachexia, Sarcopenia and Muscle
Volume	4
Issue number	1
DOIs	https://doi.org/10.1007/s13539-012-0085-3
Publication status	Published - 2013

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10.1007/s13539-012-0085-3Licence: CC BY-NC

Cite this

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title = "Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model",

abstract = "In an animal model of CHF, the expression of myostatin is significantly reduced in the skeletal muscle after application of ghrelin and most concentrations of its analogues BIM-28125 and BIM-28131 possibly due to anti-inflammatory effects.",

author = "Karsten Lenk and Sandra Palus and Robert Schur and Rakesh Datta and Jesse Dong and Culler, {Michael D.} and Stefan Anker and Jochen Springer and Gerhard Schuler and Volker Adams",

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T1 - Effect of ghrelin and its analogues, BIM-28131 and BIM-28125, on the expression of myostatin in a rat heart failure model

AU - Lenk, Karsten

AU - Palus, Sandra

AU - Schur, Robert

AU - Datta, Rakesh

AU - Dong, Jesse

AU - Culler, Michael D.

AU - Anker, Stefan

AU - Springer, Jochen

AU - Schuler, Gerhard

AU - Adams, Volker

PY - 2013

Y1 - 2013

N2 - In an animal model of CHF, the expression of myostatin is significantly reduced in the skeletal muscle after application of ghrelin and most concentrations of its analogues BIM-28125 and BIM-28131 possibly due to anti-inflammatory effects.

AB - In an animal model of CHF, the expression of myostatin is significantly reduced in the skeletal muscle after application of ghrelin and most concentrations of its analogues BIM-28125 and BIM-28131 possibly due to anti-inflammatory effects.

U2 - 10.1007/s13539-012-0085-3

DO - 10.1007/s13539-012-0085-3

M3 - Article

SN - 2190-5991

VL - 4

SP - 63

EP - 69

JO - Journal of Cachexia, Sarcopenia and Muscle

JF - Journal of Cachexia, Sarcopenia and Muscle

IS - 1

ER -