Effectiveness and costs of interventions to lower systolic blood pressure and cholesterol: a global and regional analysis on reduction of cardiovascular-disease risk

Christopher J L Murray, Jeremy A Lauer, Raymond C W Hutubessy, Louis Niessen, Niels Tomijima, Anthony Rodgers, Carlene M M Lawes, David B Evans

Research output: Contribution to journalArticlepeer-review

476 Citations (Scopus)


Cardiovascular disease accounts for much morbidity and mortality in developed countries and is becoming increasingly important in less developed regions. Systolic blood pressure above 115 mm Hg accounts for two-thirds of strokes and almost half of ischaemic heart disease cases, and cholesterol concentrations exceeding 3.8 mmol/L for 18% and 55%, respectively. We report estimates of the population health effects, and costs of selected interventions to reduce the risks associated with high cholesterol concentrations and blood pressure in areas of the world with differing epidemiological profiles.
Original languageEnglish
Pages (from-to)717-25
Number of pages9
JournalThe Lancet
Issue number9359
Publication statusPublished - 1 Mar 2003


  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Pressure
  • Cardiovascular Diseases
  • Child
  • Cost-Benefit Analysis
  • Developing Countries
  • Health Expenditures
  • Health Promotion
  • Humans
  • Hypercholesterolemia
  • Hypertension
  • Middle Aged
  • Quality-Adjusted Life Years
  • World Health

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