Effects of an exercise and hypocaloric healthy eating intervention on indices of psychological health status, hypothalamic-pituitary-adrenal axis regulation and immune function after early-stage breast cancer: a randomised controlled trial

John M Saxton, Emma J Scott, Amanda J Daley, M Nicola Woodroofe, Nanette Mutrie, Helen Crank, Hilary J Powers, Robert E Coleman

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Abstract

Many women experience emotional distress, depression and anxiety after a diagnosis of breast cancer. Psychological stress and depression have been associated with hypothalamic-pituitary-adrenal (HPA) axis dysregulation that may adversely affect immune system functioning and impact upon survival. This study investigated the effects of a lifestyle intervention on indices of psychological health status, HPA axis regulation and immune function in overweight women recovering from early-stage breast cancer treatment.
Original languageEnglish
Pages (from-to)R39
JournalBreast Cancer Research
Volume16
Issue number2
DOIs
Publication statusPublished - 14 Apr 2014

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