Effects of proton pump inhibitors on adverse gastrointestinal events in patients receiving clopidogrel: systematic review and meta-analysis

Chun Shing Kwok, Ramanpreet Singh Nijjar, Yoon Kong Loke

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

There has been recent concern regarding a possible adverse interaction between clopidogrel and proton pump inhibitors (PPIs), coupled with uncertainty as to whether PPIs genuinely help in reducing gastrointestinal (GI) harm.
Original languageEnglish
Pages (from-to)47-57
Number of pages11
JournalDrug Safety
Volume34
Issue number1
DOIs
Publication statusPublished - 1 Jan 2011

Keywords

  • Aspirin
  • Drug Interactions
  • Drug Therapy, Combination
  • Gastrointestinal Diseases
  • Humans
  • Platelet Aggregation Inhibitors
  • Proton Pump Inhibitors
  • Ticlopidine

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