Effects of proton pump inhibitors on adverse gastrointestinal events in patients receiving clopidogrel: systematic review and meta-analysis

Chun Shing Kwok; Ramanpreet Singh Nijjar; Yoon Kong Loke

doi:10.2165/11584750-000000000-00000

Effects of proton pump inhibitors on adverse gastrointestinal events in patients receiving clopidogrel: systematic review and meta-analysis

Chun Shing Kwok, Ramanpreet Singh Nijjar, Yoon Kong Loke

Research output: Contribution to journal › Article › peer-review

38 Citations (Scopus)

Abstract

There has been recent concern regarding a possible adverse interaction between clopidogrel and proton pump inhibitors (PPIs), coupled with uncertainty as to whether PPIs genuinely help in reducing gastrointestinal (GI) harm.

Original language	English
Pages (from-to)	47-57
Number of pages	11
Journal	Drug Safety
Volume	34
Issue number	1
DOIs	https://doi.org/10.2165/11584750-000000000-00000
Publication status	Published - 1 Jan 2011

Keywords

Aspirin
Drug Interactions
Drug Therapy, Combination
Gastrointestinal Diseases
Humans
Platelet Aggregation Inhibitors
Proton Pump Inhibitors
Ticlopidine

Access to Document

10.2165/11584750-000000000-00000

Cite this

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title = "Effects of proton pump inhibitors on adverse gastrointestinal events in patients receiving clopidogrel: systematic review and meta-analysis",

abstract = "There has been recent concern regarding a possible adverse interaction between clopidogrel and proton pump inhibitors (PPIs), coupled with uncertainty as to whether PPIs genuinely help in reducing gastrointestinal (GI) harm.",

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KW - Gastrointestinal Diseases

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KW - Platelet Aggregation Inhibitors

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KW - Ticlopidine

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