Effects of proton pump inhibitors on platelet function in patients receiving clopidogrel: a systematic review

Chun Shing Kwok; Yoon Kong Loke

doi:10.2165/11594900-000000000-00000

Effects of proton pump inhibitors on platelet function in patients receiving clopidogrel: a systematic review

Chun Shing Kwok, Yoon Kong Loke

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

There is considerable debate regarding the negative impact of concomitant proton pump inhibitor (PPI) therapy on the antiplatelet efficacy of clopidogrel.

Original language	English
Pages (from-to)	127-39
Number of pages	13
Journal	Drug Safety
Volume	35
Issue number	2
DOIs	https://doi.org/10.2165/11594900-000000000-00000
Publication status	Published - 1 Feb 2012

Keywords

Blood Platelets
Drug Interactions
Esomeprazole Sodium
Humans
Omeprazole
Platelet Aggregation
Platelet Aggregation Inhibitors
Proton Pump Inhibitors
Randomized Controlled Trials as Topic
Ticlopidine

Access to Document

10.2165/11594900-000000000-00000

Cite this

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title = "Effects of proton pump inhibitors on platelet function in patients receiving clopidogrel: a systematic review",

abstract = "There is considerable debate regarding the negative impact of concomitant proton pump inhibitor (PPI) therapy on the antiplatelet efficacy of clopidogrel.",

keywords = "Blood Platelets, Drug Interactions, Esomeprazole Sodium, Humans, Omeprazole, Platelet Aggregation, Platelet Aggregation Inhibitors, Proton Pump Inhibitors, Randomized Controlled Trials as Topic, Ticlopidine",

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KW - Blood Platelets

KW - Drug Interactions

KW - Esomeprazole Sodium

KW - Humans

KW - Omeprazole

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KW - Platelet Aggregation Inhibitors

KW - Proton Pump Inhibitors

KW - Randomized Controlled Trials as Topic

KW - Ticlopidine

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