Efficacy and safety of filgotinib as induction and maintenance therapy for Crohn's disease (DIVERSITY): a phase 3, double-blind, randomised, placebo-controlled trial

Séverine Vermeire, Stefan Schreiber, David T. Rubin, Geert D'Haens, Walter Reinisch, Mamoru Watanabe, Rajiv Mehta, Xavier Roblin, Ian Beales, Piotr Gietka, Toshifumi Hibi, Ihor Hospodarskyy, Timothy Ritter, Mark C. Genovese, Paul Kwon, Eva Santermans, Franck-Olivier Le Brun, Rahul Barron, Tomasz Masior, Silvio Danese

Research output: Contribution to journalArticlepeer-review

Abstract

There is a need for efficacious therapies for patients with Crohn's disease that are better tolerated and more durable than available treatments. We aimed to evaluate the efficacy and safety of filgotinib, an oral Janus kinase 1 preferential inhibitor, for treating Crohn's disease.
Original languageEnglish
Pages (from-to)138-153
Number of pages16
JournalThe Lancet Gastroenterology & Hepatology
Volume10
Issue number2
Early online date2 Dec 2024
DOIs
Publication statusE-pub ahead of print - 2 Dec 2024

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