Efficient gene transfection with functionalised multicalixarenes

R. Lalor, J. L. DiGesso, A. Mueller, S. E. Matthews

Research output: Contribution to journalArticlepeer-review

58 Citations (Scopus)

Abstract

Novel amino-functionalised multicalixarenes have been synthesised which show low cellular toxicity, effective DNA binding and, when featuring aliphatic amines, are efficient gene transfection agents.
Original languageEnglish
Pages (from-to)4907-4909
Number of pages3
JournalChemical Communications
Issue number46
DOIs
Publication statusPublished - 2007

Keywords

  • BINDING-PROPERTIES
  • CONFORMATIONAL
  • CALIXARENES
  • DENDRIMERS
  • DNA
  • ION-CHANNEL
  • UPPER RIM
  • SOLID LIPID NANOPARTICLES
  • ISOMERS
  • CHEMOKINE RECEPTOR CCR5
  • DELIVERY

Cite this