Electrical and mechanical components of dyssynchrony in heart failure patients with normal QRS duration and left bundle-branch block: Impact of left and biventricular pacing

Mark S. Turner; Rob A. Bleasdale; Dragos Vinereanu; Catherine E. Mumford; Vince Paul; Alan G. Fraser; Michael P. Frenneaux

doi:10.1161/01.CIR.0000131184.40893.40

Electrical and mechanical components of dyssynchrony in heart failure patients with normal QRS duration and left bundle-branch block: Impact of left and biventricular pacing

Mark S. Turner, Rob A. Bleasdale, Dragos Vinereanu, Catherine E. Mumford, Vince Paul, Alan G. Fraser, Michael P. Frenneaux

Research output: Contribution to journal › Article › peer-review

145 Citations (Scopus)

Abstract

Resynchronization pacing is an effective symptomatic treatment for heart failure patients with prolongation of the QRS duration (QRSd). Dyssynchronous contraction of the left ventricle is also observed with normal QRSd. We set out to determine how electrical activation of the left ventricular (LV) free wall differed between patients with left bundle-branch block (LBBB) and normal QRSd and if synchrony improved during pacing in patients with normal QRSd.

Original language	English
Pages (from-to)	2544-2549
Number of pages	6
Journal	Circulation
Volume	109
Issue number	21
DOIs	https://doi.org/10.1161/01.CIR.0000131184.40893.40
Publication status	Published - 1 Jun 2004

Keywords

Aged
Biomechanical Phenomena
Bundle-Branch Block
Cardiac Pacing, Artificial
Echocardiography, Doppler
Electrocardiography
Electrophysiology
Female
Heart Conduction System
Heart Failure
Heart Ventricles
Humans
Male
Middle Aged
Models, Cardiovascular
Myocardial Contraction
Systole
Time Factors
Ventricular Function, Left
Ventricular Function, Right

Access to Document

10.1161/01.CIR.0000131184.40893.40

Cite this

Turner, M. S., Bleasdale, R. A., Vinereanu, D., Mumford, C. E., Paul, V., Fraser, A. G., & Frenneaux, M. P. (2004). Electrical and mechanical components of dyssynchrony in heart failure patients with normal QRS duration and left bundle-branch block: Impact of left and biventricular pacing. Circulation, 109(21), 2544-2549. https://doi.org/10.1161/01.CIR.0000131184.40893.40

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AU - Vinereanu, Dragos

AU - Mumford, Catherine E.

AU - Paul, Vince

AU - Fraser, Alan G.

AU - Frenneaux, Michael P.

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