Endothelium-derived nitric oxide contributes to the regulation of venous tone in humans

Daniel J. Blackman; Jayne A. Morris-Thurgood; J J Atherton; Gethin R. Ellis; Richard A. Anderson; John R. Cockcroft; Michael P. Frenneaux

doi:10.1161/01.CIR.101.2.165

Endothelium-derived nitric oxide contributes to the regulation of venous tone in humans

Daniel J. Blackman, Jayne A. Morris-Thurgood, J J Atherton, Gethin R. Ellis, Richard A. Anderson, John R. Cockcroft, Michael P. Frenneaux

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

Although nitric oxide (NO) is known to play an important part in the regulation of arterial tone, little is known about its role in veins. The aim of this study was to investigate the role of basal and stimulated NO activity in the regulation of tone of the human venous capacitance bed.

Original language	English
Pages (from-to)	165-170
Number of pages	6
Journal	Circulation
Volume	101
Issue number	2
DOIs	https://doi.org/10.1161/01.CIR.101.2.165
Publication status	Published - 18 Jan 2000

Keywords

Adult
Carbachol
Endothelium, Vascular
Enzyme Inhibitors
Female
Forearm
Humans
Hydralazine
Injections, Intra-Arterial
Male
Middle Aged
Nitric Oxide
Vascular Resistance
Vasodilator Agents
Vasomotor System
Veins
omega-N-Methylarginine

Access to Document

10.1161/01.CIR.101.2.165

Cite this

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title = "Endothelium-derived nitric oxide contributes to the regulation of venous tone in humans",

abstract = "Although nitric oxide (NO) is known to play an important part in the regulation of arterial tone, little is known about its role in veins. The aim of this study was to investigate the role of basal and stimulated NO activity in the regulation of tone of the human venous capacitance bed.",

keywords = "Adult, Carbachol, Endothelium, Vascular, Enzyme Inhibitors, Female, Forearm, Humans, Hydralazine, Injections, Intra-Arterial, Male, Middle Aged, Nitric Oxide, Vascular Resistance, Vasodilator Agents, Vasomotor System, Veins, omega-N-Methylarginine",

author = "Blackman, {Daniel J.} and Morris-Thurgood, {Jayne A.} and Atherton, {J J} and Ellis, {Gethin R.} and Anderson, {Richard A.} and Cockcroft, {John R.} and Frenneaux, {Michael P.}",

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AU - Blackman, Daniel J.

AU - Morris-Thurgood, Jayne A.

AU - Atherton, J J

AU - Ellis, Gethin R.

AU - Anderson, Richard A.

AU - Cockcroft, John R.

AU - Frenneaux, Michael P.

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KW - Adult

KW - Carbachol

KW - Endothelium, Vascular

KW - Enzyme Inhibitors

KW - Female

KW - Forearm

KW - Humans

KW - Hydralazine

KW - Injections, Intra-Arterial

KW - Male

KW - Middle Aged

KW - Nitric Oxide

KW - Vascular Resistance

KW - Vasodilator Agents

KW - Vasomotor System

KW - Veins

KW - omega-N-Methylarginine

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JO - Circulation

JF - Circulation

SN - 0009-7322

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