Endothelium-derived nitric oxide contributes to the regulation of venous tone in humans

Daniel J. Blackman, Jayne A. Morris-Thurgood, J J Atherton, Gethin R. Ellis, Richard A. Anderson, John R. Cockcroft, Michael P. Frenneaux

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36 Citations (Scopus)

Abstract

Although nitric oxide (NO) is known to play an important part in the regulation of arterial tone, little is known about its role in veins. The aim of this study was to investigate the role of basal and stimulated NO activity in the regulation of tone of the human venous capacitance bed.
Original languageEnglish
Pages (from-to)165-170
Number of pages6
JournalCirculation
Volume101
Issue number2
DOIs
Publication statusPublished - 18 Jan 2000

Keywords

  • Adult
  • Carbachol
  • Endothelium, Vascular
  • Enzyme Inhibitors
  • Female
  • Forearm
  • Humans
  • Hydralazine
  • Injections, Intra-Arterial
  • Male
  • Middle Aged
  • Nitric Oxide
  • Vascular Resistance
  • Vasodilator Agents
  • Vasomotor System
  • Veins
  • omega-N-Methylarginine

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