This article explicates the blood flow across an artery with multiple stenosis at outer wall and a thrombus at the centre. The symmetric multiple stenosis and non-symmetric multiple stenosis shapes are both considered in this study. Entropy analysis is also taken into account for a detailed study of irreversibility. The governing equations are interpreted with provided boundary conditions and exact mathematical solutions are developed. Further, these exact solutions are elucidated graphically. Streamlines show that the closed contours are symmetric in shape for symmetric multiple stenosis but non-symmetric in shape for non-symmetric multiple stenosis shape. The increase in multiple stenosis heights, increases the shear stress at wall having multiple stenosis.