Epidemiologic assessment of sugars consumption using biomarkers: Comparisons of obese and nonobese individuals in the European prospective investigation of cancer Norfolk

Sheila Bingham, Robert Luben, Ailsa Welch, Natasa Tasevska, Nick Wareham, Kay Tee Khaw

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We have previously shown that urinary sugars excretion in 24 h urine collections can serve as an independent biomarker of sugars consumption. In the European Prospective Investigation of Cancer (EPIC) Norfolk study of nutrition and cancer, this biomarker in spot urines has been assessed in a cross-sectional comparison of 404 obese individuals aged 45 to 75 years with a body mass index (BMI) of >30 kg/m(2) and 471 normal weight individuals aged 45 to 75 years with a BMI of 30 were significantly elevated for urinary sucrose [trend per milligram per liter quintile, 1.13; 95% confidence interval (95% CI), 1.02-1.25; P = 0.016], and the odds ratio for urinary sucrose/fructose ratio was highly significant (trend per quintile, 1.264; 95% CI, 1.142-1.401; P
Original languageEnglish
Pages (from-to)1651-1654
Number of pages4
JournalCancer Epidemiology, Biomarkers & Prevention
Issue number8
Publication statusPublished - Aug 2007


  • Aged
  • Ascorbic Acid
  • Biological Markers
  • Body Mass Index
  • Body Weight
  • Cohort Studies
  • Cross-Sectional Studies
  • Dietary Carbohydrates
  • Dietary Proteins
  • Dietary Sucrose
  • Eating
  • Epidemiologic Studies
  • Europe
  • Female
  • Food Habits
  • Fructose
  • Humans
  • Male
  • Middle Aged
  • Obesity
  • Prospective Studies
  • Vitamins

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