Epidemiology of vancomycin-resistant enterococci in Canadian hospitals (CANWARD study, 2007 to 2013)

Canadian Antimicrobial Resistance Alliance (CARA)

doi:10.1128/AAC.00384-15

Epidemiology of vancomycin-resistant enterococci in Canadian hospitals (CANWARD study, 2007 to 2013)

Canadian Antimicrobial Resistance Alliance (CARA)

Norwich Medical School

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

Abstract

Of 1,927 Enterococcus species isolates collected across Canada from 2007 to 2013, 80 (4.2%) were identified as vancomycin-resistant enterococci (VRE). VRE infections during this time tripled in Canadian hospitals, from 1.8% to 6.0% (P = 0.03). All VRE were Enterococcus faecium, with 90% possessing vanA. The prevalence of vanB decreased from 37.5% in 2007 to 0% in 2013 (P < 0.05). The VRE were multidrug resistant, but 70.6%, 86.3%, and 100% were susceptible to doxycycline, linezolid, and daptomycin, respectively.

Original language	English
Pages (from-to)	4315-4317
Number of pages	3
Journal	Antimicrobial Agents and Chemotherapy
Volume	59
Issue number	7
DOIs	https://doi.org/10.1128/AAC.00384-15
Publication status	Published - 1 Jul 2015

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SDG 3 Good Health and Well-being

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10.1128/AAC.00384-15

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title = "Epidemiology of vancomycin-resistant enterococci in Canadian hospitals (CANWARD study, 2007 to 2013)",

abstract = "Of 1,927 Enterococcus species isolates collected across Canada from 2007 to 2013, 80 (4.2\%) were identified as vancomycin-resistant enterococci (VRE). VRE infections during this time tripled in Canadian hospitals, from 1.8\% to 6.0\% (P = 0.03). All VRE were Enterococcus faecium, with 90\% possessing vanA. The prevalence of vanB decreased from 37.5\% in 2007 to 0\% in 2013 (P < 0.05). The VRE were multidrug resistant, but 70.6\%, 86.3\%, and 100\% were susceptible to doxycycline, linezolid, and daptomycin, respectively.",

author = "Simner, \{P. J.\} and H. Adam and M. Baxter and M. McCracken and G. Golding and Karlowsky, \{J. A.\} and K. Nichol and P. Lagac{\'e}-Wiens and Gilmour, \{M. W.\} and Hoban, \{D. J.\} and Zhanel, \{G. G.\} and \{Canadian Antimicrobial Resistance Alliance (CARA)\}",

year = "2015",

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doi = "10.1128/AAC.00384-15",

language = "English",

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journal = "Antimicrobial Agents and Chemotherapy",

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publisher = "American Society for Microbiology",

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TY - JOUR

T1 - Epidemiology of vancomycin-resistant enterococci in Canadian hospitals (CANWARD study, 2007 to 2013)

AU - Simner, P. J.

AU - Adam, H.

AU - Baxter, M.

AU - McCracken, M.

AU - Golding, G.

AU - Karlowsky, J. A.

AU - Nichol, K.

AU - Lagacé-Wiens, P.

AU - Gilmour, M. W.

AU - Hoban, D. J.

AU - Zhanel, G. G.

AU - Canadian Antimicrobial Resistance Alliance (CARA)

PY - 2015/7/1

Y1 - 2015/7/1

N2 - Of 1,927 Enterococcus species isolates collected across Canada from 2007 to 2013, 80 (4.2%) were identified as vancomycin-resistant enterococci (VRE). VRE infections during this time tripled in Canadian hospitals, from 1.8% to 6.0% (P = 0.03). All VRE were Enterococcus faecium, with 90% possessing vanA. The prevalence of vanB decreased from 37.5% in 2007 to 0% in 2013 (P < 0.05). The VRE were multidrug resistant, but 70.6%, 86.3%, and 100% were susceptible to doxycycline, linezolid, and daptomycin, respectively.

AB - Of 1,927 Enterococcus species isolates collected across Canada from 2007 to 2013, 80 (4.2%) were identified as vancomycin-resistant enterococci (VRE). VRE infections during this time tripled in Canadian hospitals, from 1.8% to 6.0% (P = 0.03). All VRE were Enterococcus faecium, with 90% possessing vanA. The prevalence of vanB decreased from 37.5% in 2007 to 0% in 2013 (P < 0.05). The VRE were multidrug resistant, but 70.6%, 86.3%, and 100% were susceptible to doxycycline, linezolid, and daptomycin, respectively.

UR - https://www.scopus.com/pages/publications/84931292097

U2 - 10.1128/AAC.00384-15

DO - 10.1128/AAC.00384-15

M3 - Article

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AN - SCOPUS:84931292097

SN - 0066-4804

VL - 59

SP - 4315

EP - 4317

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 7

ER -

Epidemiology of vancomycin-resistant enterococci in Canadian hospitals (CANWARD study, 2007 to 2013)

Abstract

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