Epoxide formation in the Friedel-Crafts reaction of adipoyl chloride and bromobenzene

Andrew N. Cammidge, Richard D. Kelsey, Amy S. H. King

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The aluminium chloride catalysed Friedel-Crafts reaction between adipoyl chloride and bromobenzene has been re-examined. At elevated temperatures a number of side products are produced including a cyclopentane epoxide. The structure of this epoxide was elucidated by nmr and ir spectroscopy and its stereochemistry confirmed by x-ray crystallography.
Original languageEnglish
Pages (from-to)147-148
Number of pages2
JournalTetrahedron Letters
Volume40
Issue number1
DOIs
Publication statusPublished - 1 Jan 1999

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