ESPEN endorsed recommendations.  Definition and classification of intestinal failure in adults

Loris Pironi; Jann Arends; Janet Baxter; Federico Bozzetti; Rosa Burgos Peláez; Cristina Cuerda; Alastair Forbes; Simon Gabe; Lyn Gillanders; Mette Holst; Palle Bekker Jeppesen; Francisca Joly; Darlene Kelly; Stanislaw Klek; Øivind Irtun; Sw Olde Damink; Marina Panisic; Henrik Højgaard Rasmussen; Michael Staun; Kinga Szczepanek; André Van Gossum; Geert Wanten; Stéphane Michel Schneider; Jon Shaffer

doi:10.1016/j.clnu.2014.08.017

ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults

Loris Pironi, Jann Arends, Janet Baxter, Federico Bozzetti, Rosa Burgos Peláez, Cristina Cuerda, Alastair Forbes, Simon Gabe, Lyn Gillanders, Mette Holst, Palle Bekker Jeppesen, Francisca Joly, Darlene Kelly, Stanislaw Klek, Øivind Irtun, Sw Olde Damink, Marina Panisic, Henrik Højgaard Rasmussen, Michael Staun, Kinga SzczepanekAndré Van Gossum, Geert Wanten, Stéphane Michel Schneider, Jon Shaffer

Research output: Contribution to journal › Article › peer-review

484 Citations (Scopus)

Abstract

Background & aims:
Intestinal failure (IF) is not included in the list of PubMed Mesh terms, as failure is the term describing a state of non functioning of other organs, and as such is not well recognized. No scientific society has yet devised a formal definition and classification of IF. The European Society for Clinical Nutrition and Metabolism guideline committee endorsed its “home artificial nutrition and chronic IF” and “acute IF” special interest groups to write recommendations on these issues.

Methods:
After a Medline Search, in December 2013, for “intestinal failure” and “review”[Publication Type], the project was developed using the Delphi round methodology. The final consensus was reached on March 2014, after 5 Delphi rounds and two live meetings.

Results:
The recommendations comprise the definition of IF, a functional and a pathophysiological classification for both acute and chronic IF and a clinical classification of chronic IF. IF was defined as “the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth”.

Conclusions:
This formal definition and classification of IF, will facilitate communication and cooperation among professionals in clinical practice, organization and management, and research.

Original language	English
Article number	25311444
Pages (from-to)	171-180
Number of pages	10
Journal	Clinical Nutrition
Volume	34
Issue number	2
Early online date	21 Sep 2014
DOIs	https://doi.org/10.1016/j.clnu.2014.08.017
Publication status	Published - Apr 2015

Keywords

intestinal failure
HPN
TPN
Short bowel syndrome
Chronic intestinal pseudo-obstruction
Enterocutaneous fistulas
Home parenteral nutrition
Intestinal transplantation

Access to Document

10.1016/j.clnu.2014.08.017

Cite this

Pironi, L., Arends, J., Baxter, J., Bozzetti, F., Burgos Peláez, R., Cuerda, C., Forbes, A., Gabe, S., Gillanders, L., Holst, M., Jeppesen, P. B., Joly, F., Kelly, D., Klek, S., Irtun, Ø., Olde Damink, S., Panisic, M., Rasmussen, H. H., Staun, M., ... Shaffer, J. (2015). ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults. Clinical Nutrition, 34(2), 171-180. [25311444]. https://doi.org/10.1016/j.clnu.2014.08.017

Pironi, Loris ; Arends, Jann ; Baxter, Janet ; Bozzetti, Federico ; Burgos Peláez, Rosa ; Cuerda, Cristina ; Forbes, Alastair ; Gabe, Simon ; Gillanders, Lyn ; Holst, Mette ; Jeppesen, Palle Bekker ; Joly, Francisca ; Kelly, Darlene ; Klek, Stanislaw ; Irtun, Øivind ; Olde Damink, Sw ; Panisic, Marina ; Rasmussen, Henrik Højgaard ; Staun, Michael ; Szczepanek, Kinga ; Van Gossum, André ; Wanten, Geert ; Schneider, Stéphane Michel ; Shaffer, Jon. / ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults. In: Clinical Nutrition. 2015 ; Vol. 34, No. 2. pp. 171-180.

@article{62106f6be75d41ed8afae8094b5ceabe,

title = "ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults",

abstract = "Background & aims: Intestinal failure (IF) is not included in the list of PubMed Mesh terms, as failure is the term describing a state of non functioning of other organs, and as such is not well recognized. No scientific society has yet devised a formal definition and classification of IF. The European Society for Clinical Nutrition and Metabolism guideline committee endorsed its “home artificial nutrition and chronic IF” and “acute IF” special interest groups to write recommendations on these issues.Methods: After a Medline Search, in December 2013, for “intestinal failure” and “review”[Publication Type], the project was developed using the Delphi round methodology. The final consensus was reached on March 2014, after 5 Delphi rounds and two live meetings.Results: The recommendations comprise the definition of IF, a functional and a pathophysiological classification for both acute and chronic IF and a clinical classification of chronic IF. IF was defined as “the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth”.Conclusions: This formal definition and classification of IF, will facilitate communication and cooperation among professionals in clinical practice, organization and management, and research.",

keywords = "intestinal failure, HPN, TPN, Short bowel syndrome, Chronic intestinal pseudo-obstruction, Enterocutaneous fistulas, Home parenteral nutrition, Intestinal transplantation",

author = "Loris Pironi and Jann Arends and Janet Baxter and Federico Bozzetti and {Burgos Pel{\'a}ez}, Rosa and Cristina Cuerda and Alastair Forbes and Simon Gabe and Lyn Gillanders and Mette Holst and Jeppesen, {Palle Bekker} and Francisca Joly and Darlene Kelly and Stanislaw Klek and {\O}ivind Irtun and {Olde Damink}, Sw and Marina Panisic and Rasmussen, {Henrik H{\o}jgaard} and Michael Staun and Kinga Szczepanek and {Van Gossum}, Andr{\'e} and Geert Wanten and Schneider, {St{\'e}phane Michel} and Jon Shaffer",

note = "Copyright {\textcopyright} 2014 The Authors. Licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported (CC BY-NC-SA 3.0) ",

year = "2015",

month = apr,

doi = "10.1016/j.clnu.2014.08.017",

language = "English",

volume = "34",

pages = "171--180",

journal = "Clinical Nutrition",

issn = "0261-5614",

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Pironi, L, Arends, J, Baxter, J, Bozzetti, F, Burgos Peláez, R, Cuerda, C, Forbes, A, Gabe, S, Gillanders, L, Holst, M, Jeppesen, PB, Joly, F, Kelly, D, Klek, S, Irtun, Ø, Olde Damink, S, Panisic, M, Rasmussen, HH, Staun, M, Szczepanek, K, Van Gossum, A, Wanten, G, Schneider, SM & Shaffer, J 2015, 'ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults', Clinical Nutrition, vol. 34, no. 2, 25311444, pp. 171-180. https://doi.org/10.1016/j.clnu.2014.08.017

ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults. / Pironi, Loris; Arends, Jann; Baxter, Janet; Bozzetti, Federico; Burgos Peláez, Rosa; Cuerda, Cristina; Forbes, Alastair; Gabe, Simon; Gillanders, Lyn; Holst, Mette; Jeppesen, Palle Bekker; Joly, Francisca; Kelly, Darlene; Klek, Stanislaw; Irtun, Øivind; Olde Damink, Sw; Panisic, Marina; Rasmussen, Henrik Højgaard; Staun, Michael; Szczepanek, Kinga; Van Gossum, André; Wanten, Geert; Schneider, Stéphane Michel; Shaffer, Jon.

In: Clinical Nutrition, Vol. 34, No. 2, 25311444, 04.2015, p. 171-180.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults

AU - Pironi, Loris

AU - Arends, Jann

AU - Baxter, Janet

AU - Bozzetti, Federico

AU - Burgos Peláez, Rosa

AU - Cuerda, Cristina

AU - Forbes, Alastair

AU - Gabe, Simon

AU - Gillanders, Lyn

AU - Holst, Mette

AU - Jeppesen, Palle Bekker

AU - Joly, Francisca

AU - Kelly, Darlene

AU - Klek, Stanislaw

AU - Irtun, Øivind

AU - Olde Damink, Sw

AU - Panisic, Marina

AU - Rasmussen, Henrik Højgaard

AU - Staun, Michael

AU - Szczepanek, Kinga

AU - Van Gossum, André

AU - Wanten, Geert

AU - Schneider, Stéphane Michel

AU - Shaffer, Jon

PY - 2015/4

Y1 - 2015/4

N2 - Background & aims: Intestinal failure (IF) is not included in the list of PubMed Mesh terms, as failure is the term describing a state of non functioning of other organs, and as such is not well recognized. No scientific society has yet devised a formal definition and classification of IF. The European Society for Clinical Nutrition and Metabolism guideline committee endorsed its “home artificial nutrition and chronic IF” and “acute IF” special interest groups to write recommendations on these issues.Methods: After a Medline Search, in December 2013, for “intestinal failure” and “review”[Publication Type], the project was developed using the Delphi round methodology. The final consensus was reached on March 2014, after 5 Delphi rounds and two live meetings.Results: The recommendations comprise the definition of IF, a functional and a pathophysiological classification for both acute and chronic IF and a clinical classification of chronic IF. IF was defined as “the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth”.Conclusions: This formal definition and classification of IF, will facilitate communication and cooperation among professionals in clinical practice, organization and management, and research.

AB - Background & aims: Intestinal failure (IF) is not included in the list of PubMed Mesh terms, as failure is the term describing a state of non functioning of other organs, and as such is not well recognized. No scientific society has yet devised a formal definition and classification of IF. The European Society for Clinical Nutrition and Metabolism guideline committee endorsed its “home artificial nutrition and chronic IF” and “acute IF” special interest groups to write recommendations on these issues.Methods: After a Medline Search, in December 2013, for “intestinal failure” and “review”[Publication Type], the project was developed using the Delphi round methodology. The final consensus was reached on March 2014, after 5 Delphi rounds and two live meetings.Results: The recommendations comprise the definition of IF, a functional and a pathophysiological classification for both acute and chronic IF and a clinical classification of chronic IF. IF was defined as “the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or water and electrolytes, such that intravenous supplementation is required to maintain health and/or growth”.Conclusions: This formal definition and classification of IF, will facilitate communication and cooperation among professionals in clinical practice, organization and management, and research.

KW - intestinal failure

KW - HPN

KW - TPN

KW - Short bowel syndrome

KW - Chronic intestinal pseudo-obstruction

KW - Enterocutaneous fistulas

KW - Home parenteral nutrition

KW - Intestinal transplantation

U2 - 10.1016/j.clnu.2014.08.017

DO - 10.1016/j.clnu.2014.08.017

M3 - Article

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SP - 171

EP - 180

JO - Clinical Nutrition

JF - Clinical Nutrition

SN - 0261-5614

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