Estimating risks of common complex diseases across genetic and environmental factors: the example of Crohn disease

C M Lewis, S C L Whitwell, A Forbes, J Sanderson, C G Mathew, T M Marteau

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Progress has been made in identifying mutations that confer susceptibility to complex diseases, with the prospect that these genetic risks might be used in determining individual disease risk.
Original languageEnglish
Pages (from-to)689-694
Number of pages6
JournalJournal of Medical Genetics
Volume44
Issue number11
DOIs
Publication statusPublished - Nov 2007

Keywords

  • Adolescent
  • Adult
  • Bayes Theorem
  • Colitis, Ulcerative
  • Crohn Disease
  • Environmental Exposure
  • Europe
  • Family Health
  • Female
  • Gene Dosage
  • Genetic Heterogeneity
  • Genetic Predisposition to Disease
  • Humans
  • Male
  • Models, Genetic
  • Nod2 Signaling Adaptor Protein
  • Parents
  • Risk
  • Siblings
  • Smoking

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