Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa

Elizabeth Shayo; Marie Claire Van Hout; Josephine Birungi; Anupam Garrib; Sokoine Kivuyo; Sayoki Mfinanga; Moffat J. Nyrienda; Ivan Namakoola; Joseph Okebe; Kaushik Ramaiya; Max Oscar Bachmann; Walter Cullen; Jeffrey V. Lazarus; Geoff Gill; Tinevimbo Shiri; Dominic Bukenya; Hazel Snell; Mastula Nanfuka; Luis E. Cuevas; Meshack Shimwela; Gerald Mutungi; Joshua Musinguzi; Janneth Mghamba; Kenneth Mugisha; Shabbar Jaffar; Peter G. Smith; Nelson Kaulukusi Sewankambo

doi:10.1136/bmjgh-2019-002193

Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa

Elizabeth Shayo, Marie Claire Van Hout, Josephine Birungi, Anupam Garrib, Sokoine Kivuyo, Sayoki Mfinanga, Moffat J. Nyrienda, Ivan Namakoola, Joseph Okebe, Kaushik Ramaiya, Max Oscar Bachmann, Walter Cullen, Jeffrey V. Lazarus, Geoff Gill, Tinevimbo Shiri, Dominic Bukenya, Hazel Snell, Mastula Nanfuka, Luis E. Cuevas, Meshack ShimwelaGerald Mutungi, Joshua Musinguzi, Janneth Mghamba, Kenneth Mugisha, Shabbar Jaffar, Peter G. Smith, Nelson Kaulukusi Sewankambo

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Abstract

Conducting intervention studies in Africa, where medicines supply for chronic conditions is inequitable and patchy, raises major ethical issues.

Here we discuss what should the ethical approach be for a research programme in terms of provision of a steady and sustainable supply of medicines for patients with diabetes and hypertension.

Original language	English
Article number	e002193
Journal	BMJ Global Health
Volume	5
Issue number	7
Early online date	6 Jul 2020
DOIs	https://doi.org/10.1136/bmjgh-2019-002193
Publication status	Published - 6 Jul 2020

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10.1136/bmjgh-2019-002193Licence: CC BY-NC

Published_VersionFinal published version, 336 KBLicence: CC BY-NC

Max Bachmann
- M.Bachmannuea.acuk
- Norwich Medical School - Professor of Health Services Research
- Norwich Institute for Healthy Aging - Member
- Population Health - Member
- Norwich Epidemiology Centre - Member
- Health Services and Primary Care - Member
Person: Research Group Member, Research Centre Member, Academic, Teaching & Research

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Shayo, E., Van Hout, M. C., Birungi, J., Garrib, A., Kivuyo, S., Mfinanga, S., Nyrienda, M. J., Namakoola, I., Okebe, J., Ramaiya, K., Bachmann, M. O., Cullen, W., Lazarus, J. V., Gill, G., Shiri, T., Bukenya, D., Snell, H., Nanfuka, M., Cuevas, L. E., ... Sewankambo, N. K. (2020). Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa. BMJ Global Health, 5(7), [e002193]. https://doi.org/10.1136/bmjgh-2019-002193

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title = "Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa",

abstract = "Conducting intervention studies in Africa, where medicines supply for chronic conditions is inequitable and patchy, raises major ethical issues.Here we discuss what should the ethical approach be for a research programme in terms of provision of a steady and sustainable supply of medicines for patients with diabetes and hypertension.",

author = "Elizabeth Shayo and {Van Hout}, {Marie Claire} and Josephine Birungi and Anupam Garrib and Sokoine Kivuyo and Sayoki Mfinanga and Nyrienda, {Moffat J.} and Ivan Namakoola and Joseph Okebe and Kaushik Ramaiya and Bachmann, {Max Oscar} and Walter Cullen and Lazarus, {Jeffrey V.} and Geoff Gill and Tinevimbo Shiri and Dominic Bukenya and Hazel Snell and Mastula Nanfuka and Cuevas, {Luis E.} and Meshack Shimwela and Gerald Mutungi and Joshua Musinguzi and Janneth Mghamba and Kenneth Mugisha and Shabbar Jaffar and Smith, {Peter G.} and Sewankambo, {Nelson Kaulukusi}",

year = "2020",

month = jul,

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doi = "10.1136/bmjgh-2019-002193",

language = "English",

volume = "5",

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Shayo, E, Van Hout, MC, Birungi, J, Garrib, A, Kivuyo, S, Mfinanga, S, Nyrienda, MJ, Namakoola, I, Okebe, J, Ramaiya, K, Bachmann, MO, Cullen, W, Lazarus, JV, Gill, G, Shiri, T, Bukenya, D, Snell, H, Nanfuka, M, Cuevas, LE, Shimwela, M, Mutungi, G, Musinguzi, J, Mghamba, J, Mugisha, K, Jaffar, S, Smith, PG & Sewankambo, NK 2020, 'Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa', BMJ Global Health, vol. 5, no. 7, e002193. https://doi.org/10.1136/bmjgh-2019-002193

TY - JOUR

T1 - Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa

AU - Shayo, Elizabeth

AU - Van Hout, Marie Claire

AU - Birungi, Josephine

AU - Garrib, Anupam

AU - Kivuyo, Sokoine

AU - Mfinanga, Sayoki

AU - Nyrienda, Moffat J.

AU - Namakoola, Ivan

AU - Okebe, Joseph

AU - Ramaiya, Kaushik

AU - Bachmann, Max Oscar

AU - Cullen, Walter

AU - Lazarus, Jeffrey V.

AU - Gill, Geoff

AU - Shiri, Tinevimbo

AU - Bukenya, Dominic

AU - Snell, Hazel

AU - Nanfuka, Mastula

AU - Cuevas, Luis E.

AU - Shimwela, Meshack

AU - Mutungi, Gerald

AU - Musinguzi, Joshua

AU - Mghamba, Janneth

AU - Mugisha, Kenneth

AU - Jaffar, Shabbar

AU - Smith, Peter G.

AU - Sewankambo, Nelson Kaulukusi

PY - 2020/7/6

Y1 - 2020/7/6

N2 - Conducting intervention studies in Africa, where medicines supply for chronic conditions is inequitable and patchy, raises major ethical issues.Here we discuss what should the ethical approach be for a research programme in terms of provision of a steady and sustainable supply of medicines for patients with diabetes and hypertension.

AB - Conducting intervention studies in Africa, where medicines supply for chronic conditions is inequitable and patchy, raises major ethical issues.Here we discuss what should the ethical approach be for a research programme in terms of provision of a steady and sustainable supply of medicines for patients with diabetes and hypertension.

U2 - 10.1136/bmjgh-2019-002193

DO - 10.1136/bmjgh-2019-002193

M3 - Article

C2 - 32636311

VL - 5

JO - BMJ Global Health

JF - BMJ Global Health

SN - 2059-7908

IS - 7

M1 - e002193

ER -

Ethical issues in intervention studies on the prevention and management of diabetes and hypertension in sub-Saharan Africa

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Max Bachmann

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