Ethnic differences in the relationship between fasting leptin and BMI in children

S. E. Moore; A. Falorni; V. Bini; A. J. C. Fulford; M. A. O'Connell; A. M. Prentice

doi:10.1038/sj.ijo.0802484

Ethnic differences in the relationship between fasting leptin and BMI in children

S. E. Moore, A. Falorni, V. Bini, A. J. C. Fulford, M. A. O'Connell, A. M. Prentice

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

OBJECTIVE: To compare the relationship between fasting serum leptin levels and body mass index (BMI) in children from different ethnic groups. SUBJECTS: Children aged 6 - 10 y from rural Gambia (n = 471) and central Italy ( n = 839). MEASUREMENTS: Anthropometry ( z- score of BMI) and fasting serum leptin concentrations. RESULTS: The Italian children had significantly higher mean BMI z- scores than the Gambian children ( males: Italy 1.58, Gambia - 1.44, Pless than or equal to0.0001; females: Italy 1.33, Gambia - 1.42, Pless than or equal to0.0001) and significantly higher serum leptin concentrations ( males: Italy 8.86 ng ml(-1), Gambia 1.78 ng ml(-1), Pless than or equal to0.0001; females: Italy 11.31 ng ml(-1), Gambia 2.22 ng ml(-1), Pless than or equal to0.0001). A significantly different relationship was observed between z- score of BMI and serum leptin levels in the Gambian and the Italian children for both boys and girls. CONCLUSION: A different relationship exists between z- score of BMI and leptin levels in these two groups of children from very diverse ethnic backgrounds. Future studies using detailed measures of body composition and energy balance are needed to help understand this relationship.

Original language	English
Pages (from-to)	17-21
Number of pages	5
Journal	International Journal of Obesity
Volume	28
Issue number	1
DOIs	https://doi.org/10.1038/sj.ijo.0802484
Publication status	Published - 2004

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10.1038/sj.ijo.0802484

Cite this

@article{cc6b9fe2ff77471daa822331bf140742,

title = "Ethnic differences in the relationship between fasting leptin and BMI in children",

abstract = "OBJECTIVE: To compare the relationship between fasting serum leptin levels and body mass index (BMI) in children from different ethnic groups. SUBJECTS: Children aged 6 - 10 y from rural Gambia (n = 471) and central Italy ( n = 839). MEASUREMENTS: Anthropometry ( z- score of BMI) and fasting serum leptin concentrations. RESULTS: The Italian children had significantly higher mean BMI z- scores than the Gambian children ( males: Italy 1.58, Gambia - 1.44, Pless than or equal to0.0001; females: Italy 1.33, Gambia - 1.42, Pless than or equal to0.0001) and significantly higher serum leptin concentrations ( males: Italy 8.86 ng ml(-1), Gambia 1.78 ng ml(-1), Pless than or equal to0.0001; females: Italy 11.31 ng ml(-1), Gambia 2.22 ng ml(-1), Pless than or equal to0.0001). A significantly different relationship was observed between z- score of BMI and serum leptin levels in the Gambian and the Italian children for both boys and girls. CONCLUSION: A different relationship exists between z- score of BMI and leptin levels in these two groups of children from very diverse ethnic backgrounds. Future studies using detailed measures of body composition and energy balance are needed to help understand this relationship.",

author = "Moore, {S. E.} and A. Falorni and V. Bini and Fulford, {A. J. C.} and O'Connell, {M. A.} and Prentice, {A. M.}",

year = "2004",

doi = "10.1038/sj.ijo.0802484",

language = "English",

volume = "28",

pages = "17--21",

journal = "International Journal of Obesity",

issn = "0307-0565",

publisher = "Nature Publishing Group",

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TY - JOUR

T1 - Ethnic differences in the relationship between fasting leptin and BMI in children

AU - Moore, S. E.

AU - Falorni, A.

AU - Bini, V.

AU - Fulford, A. J. C.

AU - O'Connell, M. A.

AU - Prentice, A. M.

PY - 2004

Y1 - 2004

N2 - OBJECTIVE: To compare the relationship between fasting serum leptin levels and body mass index (BMI) in children from different ethnic groups. SUBJECTS: Children aged 6 - 10 y from rural Gambia (n = 471) and central Italy ( n = 839). MEASUREMENTS: Anthropometry ( z- score of BMI) and fasting serum leptin concentrations. RESULTS: The Italian children had significantly higher mean BMI z- scores than the Gambian children ( males: Italy 1.58, Gambia - 1.44, Pless than or equal to0.0001; females: Italy 1.33, Gambia - 1.42, Pless than or equal to0.0001) and significantly higher serum leptin concentrations ( males: Italy 8.86 ng ml(-1), Gambia 1.78 ng ml(-1), Pless than or equal to0.0001; females: Italy 11.31 ng ml(-1), Gambia 2.22 ng ml(-1), Pless than or equal to0.0001). A significantly different relationship was observed between z- score of BMI and serum leptin levels in the Gambian and the Italian children for both boys and girls. CONCLUSION: A different relationship exists between z- score of BMI and leptin levels in these two groups of children from very diverse ethnic backgrounds. Future studies using detailed measures of body composition and energy balance are needed to help understand this relationship.

AB - OBJECTIVE: To compare the relationship between fasting serum leptin levels and body mass index (BMI) in children from different ethnic groups. SUBJECTS: Children aged 6 - 10 y from rural Gambia (n = 471) and central Italy ( n = 839). MEASUREMENTS: Anthropometry ( z- score of BMI) and fasting serum leptin concentrations. RESULTS: The Italian children had significantly higher mean BMI z- scores than the Gambian children ( males: Italy 1.58, Gambia - 1.44, Pless than or equal to0.0001; females: Italy 1.33, Gambia - 1.42, Pless than or equal to0.0001) and significantly higher serum leptin concentrations ( males: Italy 8.86 ng ml(-1), Gambia 1.78 ng ml(-1), Pless than or equal to0.0001; females: Italy 11.31 ng ml(-1), Gambia 2.22 ng ml(-1), Pless than or equal to0.0001). A significantly different relationship was observed between z- score of BMI and serum leptin levels in the Gambian and the Italian children for both boys and girls. CONCLUSION: A different relationship exists between z- score of BMI and leptin levels in these two groups of children from very diverse ethnic backgrounds. Future studies using detailed measures of body composition and energy balance are needed to help understand this relationship.

U2 - 10.1038/sj.ijo.0802484

DO - 10.1038/sj.ijo.0802484

M3 - Article

VL - 28

SP - 17

EP - 21

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - 1

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