Abstract
Osteoarthritis (OA) and osteoporosis are often considered to lie at opposite ends of a spectrum of bone phenotypes. Lumbar degenerative disc disease (LDD) may be associated with low back pain (LBP) and is similar in many ways to OA. LDD is reported in small studies to be associated with increased spine bone mineral density (BMD). The present work aimed to confirm this association in a large population sample using MRI and explore the relationship further, in particular to determine whether it is mediated genetically.
Original language | English |
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Pages (from-to) | 2102-2106 |
Number of pages | 5 |
Journal | Annals of the Rheumatic Diseases |
Volume | 69 |
Issue number | 12 |
DOIs | |
Publication status | Published - Dec 2010 |
Keywords
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Bone Density
- Diseases in Twins
- Epidemiologic Methods
- Female
- Genetic Predisposition to Disease
- Hip Joint
- Humans
- Intervertebral Disc Degeneration
- Lumbar Vertebrae
- Magnetic Resonance Imaging
- Middle Aged
- Young Adult