Evolutionary trade-offs at the Arabidopsis WRR4A resistance locus underpin alternate Albugo candida race recognition specificities

Baptiste Castel, Sebastian Fairhead, Oliver J. Furzer, Amey Redkar, Shanshan Wang, Volkan Cevik, Eric B. Holub, Jonathan D. G. Jones

Research output: Contribution to journalArticle

Abstract

The oomycete Albugo candida causes white rust of Brassicaceae, including vegetable and oilseed crops, and wild relatives such as Arabidopsis thaliana. Novel White Rust Resistance (WRR) genes from Arabidopsis enable new insights into plant/parasite co-evolution. WRR4A from Arabidopsis accession Columbia (Col-0) provides resistance to many but not all white rust races, and encodes a nucleotide-binding, leucine-rich repeat immune receptor. Col-0 WRR4A resistance is broken by AcEx1, an isolate of A. candida. We identified an allele of WRR4A in Arabidopsis accession Øystese-0 (Oy-0) and other accessions that confers full resistance to AcEx1. WRR4A Oy-0 carries a C-terminal extension required for recognition of AcEx1, but reduces recognition of several effectors recognized by the WRR4A Col-0 allele. WRR4A Oy-0 confers full resistance to AcEx1 when expressed in the oilseed crop Camelina sativa.

Original languageEnglish
JournalThe Plant Journal
Early online date28 Jun 2021
DOIs
Publication statusE-pub ahead of print - 28 Jun 2021

Keywords

  • Arabidopsis thaliana
  • NLR
  • camelina
  • crop protection
  • effector recognition
  • evolution
  • immunity
  • natural variation
  • resistance gene

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