Exchange of valine-oxygen during the biosynthesis of δ-(L-α- aminoadipoyl)-L-cysteinyl-D-valine

Jack E. Baldwin, Robert A. Field, Christopher J. Schofield

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Incubation of [18O2]valine with purified ACV synthetase from Cephalosporium acremonium gave exclusive incorporation of a single 18O label into δ-(L-α-aminoadipoyl)-L-cysteinyl-D- valine (ACV), consistent with the formation of a covalent valinoyl-ACV synthetase complex.

Original languageEnglish
Pages (from-to)1531-1532
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number21
DOIs
Publication statusPublished - 1991

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