Exchange of valine-oxygen during the biosynthesis of δ-(L-α- aminoadipoyl)-L-cysteinyl-D-valine

Jack E. Baldwin; Robert A. Field; Christopher J. Schofield

doi:10.1039/C39910001531

Exchange of valine-oxygen during the biosynthesis of δ-(L-α- aminoadipoyl)-L-cysteinyl-D-valine

Jack E. Baldwin
, Robert A. Field
, Christopher J. Schofield

School of Chemistry, Pharmacy and Pharmacology

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Incubation of [¹⁸O₂]valine with purified ACV synthetase from Cephalosporium acremonium gave exclusive incorporation of a single ¹⁸O label into δ-(L-α-aminoadipoyl)-L-cysteinyl-D- valine (ACV), consistent with the formation of a covalent valinoyl-ACV synthetase complex.

Original language	English
Pages (from-to)	1531-1532
Number of pages	2
Journal	Journal of the Chemical Society, Chemical Communications
Issue number	21
DOIs	https://doi.org/10.1039/C39910001531
Publication status	Published - 1991

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10.1039/C39910001531

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@article{93546e36ab43471d99a01d3ee85fb630,

title = "Exchange of valine-oxygen during the biosynthesis of δ-(L-α- aminoadipoyl)-L-cysteinyl-D-valine",

abstract = "Incubation of [18O2]valine with purified ACV synthetase from Cephalosporium acremonium gave exclusive incorporation of a single 18O label into δ-(L-α-aminoadipoyl)-L-cysteinyl-D- valine (ACV), consistent with the formation of a covalent valinoyl-ACV synthetase complex.",

author = "Baldwin, \{Jack E.\} and Field, \{Robert A.\} and Schofield, \{Christopher J.\}",

year = "1991",

doi = "10.1039/C39910001531",

language = "English",

pages = "1531--1532",

journal = "Journal of the Chemical Society, Chemical Communications",

issn = "0022-4936",

publisher = "Chemical Society",

number = "21",

}

TY - JOUR

T1 - Exchange of valine-oxygen during the biosynthesis of δ-(L-α- aminoadipoyl)-L-cysteinyl-D-valine

AU - Baldwin, Jack E.

AU - Field, Robert A.

AU - Schofield, Christopher J.

PY - 1991

Y1 - 1991

N2 - Incubation of [18O2]valine with purified ACV synthetase from Cephalosporium acremonium gave exclusive incorporation of a single 18O label into δ-(L-α-aminoadipoyl)-L-cysteinyl-D- valine (ACV), consistent with the formation of a covalent valinoyl-ACV synthetase complex.

AB - Incubation of [18O2]valine with purified ACV synthetase from Cephalosporium acremonium gave exclusive incorporation of a single 18O label into δ-(L-α-aminoadipoyl)-L-cysteinyl-D- valine (ACV), consistent with the formation of a covalent valinoyl-ACV synthetase complex.

UR - https://www.scopus.com/pages/publications/0025941646

U2 - 10.1039/C39910001531

DO - 10.1039/C39910001531

M3 - Article

AN - SCOPUS:0025941646

SN - 0022-4936

SP - 1531

EP - 1532

JO - Journal of the Chemical Society, Chemical Communications

JF - Journal of the Chemical Society, Chemical Communications

IS - 21

ER -

Exchange of valine-oxygen during the biosynthesis of δ-(L-α- aminoadipoyl)-L-cysteinyl-D-valine

Abstract

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