Expedient synthesis of substituted (S)-N-(α-methylbenzyl)aziridines

Sean P. Bew, David L. Hughes, Vladimir Savic, Katy M. Soapi, Martin A. Wilson

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16 Citations (Scopus)


We report for the first time that after O-acylation the conjugate addition products of (S)-N-(α-methylbenzyl)hydroxylamine undergo an efficient diastereoselective 3-exo-tet ring-closure reaction affording 2- and 2,3-disubstituted-N-alkylaziridines in good to excellent yields. © The Royal Society of Chemistry 2006.
Original languageEnglish
Pages (from-to)3513-3515
Number of pages3
JournalChemical Communications
Issue number33
Publication statusPublished - 1 Jan 2006

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