Exploring the potential of cycloidal computed tomography for advancing intraoperative specimen imaging

Oriol Roche i Morgó, Lorenzo Massimi, Tamara Suaris, Marco Endrizzi, Peter R. T. Munro, Savvas Savvidis, Glafkos Havariyoun, P. M. Sam Hawker, Alberto Astolfo, Oliver J. Larkin, Rachel L. Nelan, J. Louise Jones, Daniël M. Pelt, David Bate, Alessandro Olivo, Charlotte K. Hagen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)


A preliminary investigation into the use of cycloidal computed tomography for intraoperative specimen imaging is presented. Intraoperative imaging is applied in time-sensitive clinical settings, where obtaining a high-resolution, highquality image within minutes is paramount in evaluating the success of operations and/or the need for additional surgery. As a flexible imaging method that is compatible with x-ray phase contrast imaging, cycloidal computed tomography can provide both high spatial resolution and high image contrast, whilst keeping scan times short thanks to an effective under-sampling approach. To gather early evidence, the method was tested on resected breast and oesophageal tissue. The results, although preliminary, indicate that cycloidal imaging may indeed be beneficial for intraoperative specimen imaging, although further studies are required to confirm this potential.

Original languageEnglish
Title of host publicationProceedings Volume 11840: Developments in X-Ray Tomography XIII
EditorsBert Muller, Ge Wang
ISBN (Electronic)9781510645189
Publication statusPublished - 9 Sep 2021
EventDevelopments in X-Ray Tomography XIII 2021 - San Diego, United States
Duration: 1 Aug 20215 Aug 2021

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
ISSN (Print)0277-786X
ISSN (Electronic)1996-756X


ConferenceDevelopments in X-Ray Tomography XIII 2021
Country/TerritoryUnited States
CitySan Diego


  • Cycloidal computed tomography
  • Edge illumination
  • Intraoperative specimen imaging
  • Micro computed tomography
  • Phase contrast
  • Spatial resolution
  • Structured illumination
  • X-ray imaging

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