Factors underlying caregiver stress in frontotemporal dementia and Alzheimer's disease

Eneida Mioshi, Matt Bristow, Rachel Cook, John R. Hodges

Research output: Contribution to journalArticlepeer-review

106 Citations (Scopus)


BACKGROUND: Frontotemporal dementia (FTD) has devastating effects on patients and caregivers, yet the factors underlying caregiver stress are poorly understood.

METHODS: 108 caregivers (79 = FTD, 29 = Alzheimer's disease) participated in a postal survey. Self-report measures of perceived stress, depression, social networks, as well as patient-based measures of behaviour change and activities of daily living were completed.

RESULTS: Depression was a cardinal feature in FTD caregivers, and it accounted for more than 58% of stress scores. Both depression and stress were significantly higher than in AD. Neither the severity of behaviour changes nor functional disability explained caregiver stress.

CONCLUSION: Caregiver stress is a multidimensional construct, and FTD caregivers should receive more support than currently available. Depression plays a key role in coping ability.

Original languageEnglish
Pages (from-to)76-81
Number of pages6
JournalDementia and Geriatric Cognitive Disorders
Issue number1
Publication statusPublished - Feb 2009
Externally publishedYes


  • Activities of Daily Living
  • Aged
  • Alzheimer Disease/psychology
  • Behavior/physiology
  • Caregivers/psychology
  • Dementia/psychology
  • Depression/psychology
  • Female
  • Humans
  • Male
  • Psychometrics
  • Sex Factors
  • Social Support
  • Stress, Psychological/psychology

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