Faecal calprotectin: a noninvasive diagnostic tool and marker of severity in pouchitis

Matt W Johnson, Susan Maestranzi, Audrey M Duffy, David H Dewar, Alastair Forbes, Ingvar Bjarnason, Roy A Sherwood, Paul Ciclitira, John R Nicholls

Research output: Contribution to journalArticlepeer-review

72 Citations (Scopus)


In pouchitis, the mucosa is infiltrated by activated polymorphonuclear neutrophils capable of producing calprotectin, a stable antimicrobial myelomonocytic protein.
Original languageEnglish
Pages (from-to)174-9
Number of pages6
JournalEuropean Journal of Gastroenterology & Hepatology
Issue number3
Publication statusPublished - Mar 2008


  • Adenomatous Polyposis Coli
  • Adult
  • Biological Markers
  • Colitis, Ulcerative
  • Diagnosis, Differential
  • Endoscopy, Gastrointestinal
  • Feces
  • Female
  • Humans
  • Leukocyte L1 Antigen Complex
  • Male
  • Middle Aged
  • Pouchitis
  • Sensitivity and Specificity
  • Severity of Illness Index

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