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Faecal calprotectin: a noninvasive diagnostic tool and marker of severity in pouchitis

  • Matt W Johnson
  • , Susan Maestranzi
  • , Audrey M Duffy
  • , David H Dewar
  • , Alastair Forbes
  • , Ingvar Bjarnason
  • , Roy A Sherwood
  • , Paul Ciclitira
  • , John R Nicholls

Research output: Contribution to journalArticlepeer-review

81 Citations (Scopus)

Abstract

In pouchitis, the mucosa is infiltrated by activated polymorphonuclear neutrophils capable of producing calprotectin, a stable antimicrobial myelomonocytic protein.
Original languageEnglish
Pages (from-to)174-9
Number of pages6
JournalEuropean Journal of Gastroenterology & Hepatology
Volume20
Issue number3
DOIs
Publication statusPublished - Mar 2008

Keywords

  • Adenomatous Polyposis Coli
  • Adult
  • Biological Markers
  • Colitis, Ulcerative
  • Diagnosis, Differential
  • Endoscopy, Gastrointestinal
  • Feces
  • Female
  • Humans
  • Leukocyte L1 Antigen Complex
  • Male
  • Middle Aged
  • Pouchitis
  • Sensitivity and Specificity
  • Severity of Illness Index

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