Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGF beta) receptor leads to paradoxical activation of TGF beta signalling pathways with fibrosis in transgenic mice

Christopher P. Denton; Bing Zheng; Lowri A. Evans; Shi-wen Xu; Voon H. Ong; Ivan Fisher; Konstantinos Lazaridis; David J. Abraham; Carol M. Black; Benoit de Crombrugghe

doi:10.1074/jbc.M300636200

Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGF beta) receptor leads to paradoxical activation of TGF beta signalling pathways with fibrosis in transgenic mice

Christopher P. Denton, Bing Zheng, Lowri A. Evans, Shi-wen Xu, Voon H. Ong, Ivan Fisher, Konstantinos Lazaridis, David J. Abraham, Carol M. Black, Benoit de Crombrugghe

School of Biological Sciences

Research output: Contribution to journal › Article › peer-review

121 Citations (Scopus)

Original language	English
Pages (from-to)	25109-25119
Number of pages	11
Journal	Journal of Biological Chemistry
Volume	278
Early online date	21 Apr 2003
DOIs	https://doi.org/10.1074/jbc.M300636200
Publication status	Published - 4 Jul 2003

Access to Document

10.1074/jbc.M300636200

Cite this

Denton, C. P., Zheng, B., Evans, L. A., Xu, S., Ong, V. H., Fisher, I., Lazaridis, K., Abraham, D. J., Black, C. M., & de Crombrugghe, B. (2003). Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGF beta) receptor leads to paradoxical activation of TGF beta signalling pathways with fibrosis in transgenic mice. Journal of Biological Chemistry, 278, 25109-25119. https://doi.org/10.1074/jbc.M300636200

@article{23ba69a0d0c14710bc06f7b36bdf843b,

title = "Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGF beta) receptor leads to paradoxical activation of TGF beta signalling pathways with fibrosis in transgenic mice",

author = "Denton, {Christopher P.} and Bing Zheng and Evans, {Lowri A.} and Shi-wen Xu and Ong, {Voon H.} and Ivan Fisher and Konstantinos Lazaridis and Abraham, {David J.} and Black, {Carol M.} and {de Crombrugghe}, Benoit",

year = "2003",

month = jul,

day = "4",

doi = "10.1074/jbc.M300636200",

language = "English",

volume = "278",

pages = "25109--25119",

journal = "Journal of Biological Chemistry",

issn = "0021-9258",

publisher = "American Society for Biochemistry and Molecular Biology Inc.",

}

Denton, CP, Zheng, B, Evans, LA, Xu, S, Ong, VH, Fisher, I, Lazaridis, K, Abraham, DJ, Black, CM & de Crombrugghe, B 2003, 'Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGF beta) receptor leads to paradoxical activation of TGF beta signalling pathways with fibrosis in transgenic mice', Journal of Biological Chemistry, vol. 278, pp. 25109-25119. https://doi.org/10.1074/jbc.M300636200

Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGF beta) receptor leads to paradoxical activation of TGF beta signalling pathways with fibrosis in transgenic mice. / Denton, Christopher P.; Zheng, Bing; Evans, Lowri A. et al.

In: Journal of Biological Chemistry, Vol. 278, 04.07.2003, p. 25109-25119.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGF beta) receptor leads to paradoxical activation of TGF beta signalling pathways with fibrosis in transgenic mice

AU - Denton, Christopher P.

AU - Zheng, Bing

AU - Evans, Lowri A.

AU - Xu, Shi-wen

AU - Ong, Voon H.

AU - Fisher, Ivan

AU - Lazaridis, Konstantinos

AU - Abraham, David J.

AU - Black, Carol M.

AU - de Crombrugghe, Benoit

PY - 2003/7/4

Y1 - 2003/7/4

U2 - 10.1074/jbc.M300636200

DO - 10.1074/jbc.M300636200

M3 - Article

VL - 278

SP - 25109

EP - 25119

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 0021-9258

ER -

Denton CP, Zheng B, Evans LA, Xu S, Ong VH, Fisher I et al. Fibroblast-specific expression of a kinase-deficient type II transforming growth factor beta (TGF beta) receptor leads to paradoxical activation of TGF beta signalling pathways with fibrosis in transgenic mice. Journal of Biological Chemistry. 2003 Jul 4;278:25109-25119. Epub 2003 Apr 21. doi: 10.1074/jbc.M300636200