TY - JOUR
T1 - Filamentous pathogen effectors interfering with small RNA silencing in plant hosts
AU - Ye, Wenwu
AU - Ma, Wenbo
N1 - Funding Information:
Research in the Ma laboratory is supported by the USDA-NIFA grant 2014-67013-21554 , the USDA-AES funding CA-R-PPA-7699-H , and the US NSF-PGRP grant IOS-1340001 . WY is supported by the China NSF grants 31430073 and 31401688 . We thank Dr. Yingnan Hou for critical reading of the manuscript and apologize to our colleagues whose work we were unable to cite owing to page limitations.
Publisher Copyright:
© 2016.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Filamentous eukaryotic pathogens including fungi and oomycetes are major threats of plant health. During the co-evolutionary arms race with the hosts, these pathogens have evolved a large repertoire of secreted virulence proteins, called effectors, to facilitate colonization and infection. Many effectors are believed to directly manipulate targeted processes inside the host cells; and a fundamental function of the effectors is to dampen immunity. Recent evidence suggests that the destructive oomycete pathogens in the genus Phytophthora encode RNA silencing suppressors. These effectors play an important virulence role during infection, likely through their inhibitory effect on host small RNA-mediated defense.
AB - Filamentous eukaryotic pathogens including fungi and oomycetes are major threats of plant health. During the co-evolutionary arms race with the hosts, these pathogens have evolved a large repertoire of secreted virulence proteins, called effectors, to facilitate colonization and infection. Many effectors are believed to directly manipulate targeted processes inside the host cells; and a fundamental function of the effectors is to dampen immunity. Recent evidence suggests that the destructive oomycete pathogens in the genus Phytophthora encode RNA silencing suppressors. These effectors play an important virulence role during infection, likely through their inhibitory effect on host small RNA-mediated defense.
UR - http://www.scopus.com/inward/record.url?scp=84963576888&partnerID=8YFLogxK
U2 - 10.1016/j.mib.2016.04.003
DO - 10.1016/j.mib.2016.04.003
M3 - Review article
C2 - 27104934
AN - SCOPUS:84963576888
VL - 32
SP - 1
EP - 6
JO - Current Opinion in Microbiology
JF - Current Opinion in Microbiology
SN - 1369-5274
ER -