Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

J Hampe, N J Lynch, S Daniels, S Bridger, A J Macpherson, P Stokkers, A Forbes, J E Lennard-Jones, C G Mathew, M E Curran, S Schreiber

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70 Citations (Scopus)

Abstract

Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.
Original languageEnglish
Pages (from-to)191-197
Number of pages7
JournalGut
Volume48
Issue number2
DOIs
Publication statusPublished - Feb 2001

Keywords

  • Alleles
  • Chromosome Mapping
  • Chromosomes, Human, Pair 3
  • Female
  • Genetic Markers
  • Haplotypes
  • Humans
  • Inflammatory Bowel Diseases
  • Lod Score
  • Male
  • Microsatellite Repeats
  • Phenotype
  • Polymorphism, Genetic

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