Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

J Hampe; N J Lynch; S Daniels; S Bridger; A J Macpherson; P Stokkers; A Forbes; J E Lennard-Jones; C G Mathew; M E Curran; S Schreiber

doi:10.1136/gut.48.2.191

Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

J Hampe, N J Lynch, S Daniels, S Bridger, A J Macpherson, P Stokkers, A Forbes, J E Lennard-Jones, C G Mathew, M E Curran, S Schreiber

Research output: Contribution to journal › Article › peer-review

71 Citations (Scopus)

Abstract

Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.

Original language	English
Pages (from-to)	191-197
Number of pages	7
Journal	Gut
Volume	48
Issue number	2
DOIs	https://doi.org/10.1136/gut.48.2.191
Publication status	Published - Feb 2001

Keywords

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 3
Female
Genetic Markers
Haplotypes
Humans
Inflammatory Bowel Diseases
Lod Score
Male
Microsatellite Repeats
Phenotype
Polymorphism, Genetic

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1136/gut.48.2.191

Cite this

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title = "Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease",

abstract = "Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.",

keywords = "Alleles, Chromosome Mapping, Chromosomes, Human, Pair 3, Female, Genetic Markers, Haplotypes, Humans, Inflammatory Bowel Diseases, Lod Score, Male, Microsatellite Repeats, Phenotype, Polymorphism, Genetic",

author = "J Hampe and Lynch, {N J} and S Daniels and S Bridger and Macpherson, {A J} and P Stokkers and A Forbes and Lennard-Jones, {J E} and Mathew, {C G} and Curran, {M E} and S Schreiber",

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T1 - Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

AU - Hampe, J

AU - Lynch, N J

AU - Daniels, S

AU - Bridger, S

AU - Macpherson, A J

AU - Stokkers, P

AU - Forbes, A

AU - Lennard-Jones, J E

AU - Mathew, C G

AU - Curran, M E

AU - Schreiber, S

PY - 2001/2

Y1 - 2001/2

N2 - Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.

AB - Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.

KW - Alleles

KW - Chromosome Mapping

KW - Chromosomes, Human, Pair 3

KW - Female

KW - Genetic Markers

KW - Haplotypes

KW - Humans

KW - Inflammatory Bowel Diseases

KW - Lod Score

KW - Male

KW - Microsatellite Repeats

KW - Phenotype

KW - Polymorphism, Genetic

U2 - 10.1136/gut.48.2.191

DO - 10.1136/gut.48.2.191

M3 - Article

C2 - 11156639

SN - 0017-5749

VL - 48

SP - 191

EP - 197

JO - Gut

JF - Gut

IS - 2

ER -