Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

J Hampe; N J Lynch; S Daniels; S Bridger; A J Macpherson; P Stokkers; A Forbes; J E Lennard-Jones; C G Mathew; M E Curran; S Schreiber

doi:10.1136/gut.48.2.191

Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

J Hampe
, N J Lynch
, S Daniels
, S Bridger
, A J Macpherson
, P Stokkers
, A Forbes
, J E Lennard-Jones
, C G Mathew
, M E Curran
, S Schreiber

Research output: Contribution to journal › Article › peer-review

71 Citations (Scopus)

Abstract

Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.

Original language	English
Pages (from-to)	191-197
Number of pages	7
Journal	Gut
Volume	48
Issue number	2
DOIs	https://doi.org/10.1136/gut.48.2.191
Publication status	Published - Feb 2001

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 3
Female
Genetic Markers
Haplotypes
Humans
Inflammatory Bowel Diseases
Lod Score
Male
Microsatellite Repeats
Phenotype
Polymorphism, Genetic

Access to Document

10.1136/gut.48.2.191

Cite this

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title = "Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease",

abstract = "Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.",

keywords = "Alleles, Chromosome Mapping, Chromosomes, Human, Pair 3, Female, Genetic Markers, Haplotypes, Humans, Inflammatory Bowel Diseases, Lod Score, Male, Microsatellite Repeats, Phenotype, Polymorphism, Genetic",

author = "J Hampe and Lynch, \{N J\} and S Daniels and S Bridger and Macpherson, \{A J\} and P Stokkers and A Forbes and Lennard-Jones, \{J E\} and Mathew, \{C G\} and Curran, \{M E\} and S Schreiber",

year = "2001",

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doi = "10.1136/gut.48.2.191",

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T1 - Fine mapping of the chromosome 3p susceptibility locus in inflammatory bowel disease

AU - Hampe, J

AU - Lynch, N J

AU - Daniels, S

AU - Bridger, S

AU - Macpherson, A J

AU - Stokkers, P

AU - Forbes, A

AU - Lennard-Jones, J E

AU - Mathew, C G

AU - Curran, M E

AU - Schreiber, S

PY - 2001/2

Y1 - 2001/2

N2 - Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.

AB - Genetic predisposition for inflammatory bowel disease (IBD) has been demonstrated by epidemiological and genetic linkage studies. Genetic linkage of IBD to chromosome 3 has been observed previously. A high density analysis of chromosome 3p was performed to confirm prior linkages and elucidate potential genetic associations.

KW - Alleles

KW - Chromosome Mapping

KW - Chromosomes, Human, Pair 3

KW - Female

KW - Genetic Markers

KW - Haplotypes

KW - Humans

KW - Inflammatory Bowel Diseases

KW - Lod Score

KW - Male

KW - Microsatellite Repeats

KW - Phenotype

KW - Polymorphism, Genetic

U2 - 10.1136/gut.48.2.191

DO - 10.1136/gut.48.2.191

M3 - Article

C2 - 11156639

SN - 0017-5749

VL - 48

SP - 191

EP - 197

JO - Gut

JF - Gut

IS - 2

ER -