Fk 228 derivates as hdac inhibitors

A. Ganesan; Graham Packham; Alexander Yurek-George; Alexander Richard Liam Cecil

Fk 228 derivates as hdac inhibitors

A. Ganesan (Inventor), Graham Packham (Inventor), Alexander Yurek-George (Inventor), Alexander Richard Liam Cecil (Inventor)

Research output: Patent

Abstract

Compounds which are FK228 analogues of the general formula (I) or (I/), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.

Original language	English
Patent number	WO-2006129105-A1
Publication status	Published - 2005

Cite this

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title = "Fk 228 derivates as hdac inhibitors",

abstract = "Compounds which are FK228 analogues of the general formula (I) or (I/), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.",

author = "A. Ganesan and Graham Packham and Alexander Yurek-George and Cecil, {Alexander Richard Liam}",

year = "2005",

language = "English",

type = "Patent",

note = "WO-2006129105-A1",

}

TY - PAT

T1 - Fk 228 derivates as hdac inhibitors

AU - Ganesan, A.

AU - Packham, Graham

AU - Yurek-George, Alexander

AU - Cecil, Alexander Richard Liam

PY - 2005

Y1 - 2005

N2 - Compounds which are FK228 analogues of the general formula (I) or (I/), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.

AB - Compounds which are FK228 analogues of the general formula (I) or (I/), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.

M3 - Patent

M1 - WO-2006129105-A1

ER -