Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease-FLAVURS: a randomized controlled trial

Anna L Macready, Trevor W George, Mary F Chong, Dauren S Alimbetov, Yannan Jin, Alberto Vidal, Jeremy P E Spencer, Orla B Kennedy, Kieran M Tuohy, Anne-Marie Minihane, Michael H Gordon, Julie A Lovegrove, FLAVURS Study Group

Research output: Contribution to journalArticlepeer-review

142 Citations (Scopus)


Observed associations between increased fruit and vegetable (F&V) consumption, particularly those F&Vs that are rich in flavonoids, and vascular health improvements require confirmation in adequately powered randomized controlled trials.
Original languageEnglish
Pages (from-to)479-489
Number of pages11
JournalAmerican Journal of Clinical Nutrition
Issue number3
Publication statusPublished - Mar 2014


  • Adult
  • Aged
  • Anti-Inflammatory Agents, Non-Steroidal
  • Biological Markers
  • Cardiovascular Diseases
  • Cohort Studies
  • Cytokines
  • England
  • Female
  • Flavonoids
  • Fruit
  • Humans
  • Hypertension
  • Male
  • Microvessels
  • Middle Aged
  • Risk Factors
  • Sex Characteristics
  • Single-Blind Method
  • Vascular Resistance
  • Vascular Stiffness
  • Vegetables

Cite this