Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease-FLAVURS: a randomized controlled trial

Anna L Macready; Trevor W George; Mary F Chong; Dauren S Alimbetov; Yannan Jin; Alberto Vidal; Jeremy P E Spencer; Orla B Kennedy; Kieran M Tuohy; Anne-Marie Minihane; Michael H Gordon; Julie A Lovegrove; FLAVURS Study Group

doi:10.3945/ajcn.113.074237

Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease-FLAVURS: a randomized controlled trial

Anna L Macready, Trevor W George, Mary F Chong, Dauren S Alimbetov, Yannan Jin, Alberto Vidal, Jeremy P E Spencer, Orla B Kennedy, Kieran M Tuohy, Anne-Marie Minihane, Michael H Gordon, Julie A Lovegrove, FLAVURS Study Group

Research output: Contribution to journal › Article › peer-review

158 Citations (Scopus)

Abstract

Observed associations between increased fruit and vegetable (F&V) consumption, particularly those F&Vs that are rich in flavonoids, and vascular health improvements require confirmation in adequately powered randomized controlled trials.

Original language	English
Pages (from-to)	479-489
Number of pages	11
Journal	American Journal of Clinical Nutrition
Volume	99
Issue number	3
DOIs	https://doi.org/10.3945/ajcn.113.074237
Publication status	Published - Mar 2014

Keywords

Adult
Aged
Anti-Inflammatory Agents, Non-Steroidal
Biological Markers
Cardiovascular Diseases
Cohort Studies
Cytokines
England
Female
Flavonoids
Fruit
Humans
Hypertension
Male
Microvessels
Middle Aged
Risk Factors
Sex Characteristics
Single-Blind Method
Vascular Resistance
Vascular Stiffness
Vegetables

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.3945/ajcn.113.074237

Cite this

Macready, A. L., George, T. W., Chong, M. F., Alimbetov, D. S., Jin, Y., Vidal, A., Spencer, J. P. E., Kennedy, O. B., Tuohy, K. M., Minihane, A.-M., Gordon, M. H., Lovegrove, J. A., & FLAVURS Study Group (2014). Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease-FLAVURS: a randomized controlled trial. American Journal of Clinical Nutrition, 99(3), 479-489. https://doi.org/10.3945/ajcn.113.074237

@article{1df91c9eaad541a2bb0c8611c7ab3dd5,

title = "Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease-FLAVURS: a randomized controlled trial",

abstract = "Observed associations between increased fruit and vegetable (F&V) consumption, particularly those F&Vs that are rich in flavonoids, and vascular health improvements require confirmation in adequately powered randomized controlled trials.",

keywords = "Adult, Aged, Anti-Inflammatory Agents, Non-Steroidal, Biological Markers, Cardiovascular Diseases, Cohort Studies, Cytokines, England, Female, Flavonoids, Fruit, Humans, Hypertension, Male, Microvessels, Middle Aged, Risk Factors, Sex Characteristics, Single-Blind Method, Vascular Resistance, Vascular Stiffness, Vegetables",

author = "Macready, {Anna L} and George, {Trevor W} and Chong, {Mary F} and Alimbetov, {Dauren S} and Yannan Jin and Alberto Vidal and Spencer, {Jeremy P E} and Kennedy, {Orla B} and Tuohy, {Kieran M} and Anne-Marie Minihane and Gordon, {Michael H} and Lovegrove, {Julie A} and {FLAVURS Study Group}",

year = "2014",

month = mar,

doi = "10.3945/ajcn.113.074237",

language = "English",

volume = "99",

pages = "479--489",

journal = "American Journal of Clinical Nutrition",

issn = "0002-9165",

publisher = "Elsevier",

number = "3",

}

Macready, AL, George, TW, Chong, MF, Alimbetov, DS, Jin, Y, Vidal, A, Spencer, JPE, Kennedy, OB, Tuohy, KM, Minihane, A-M, Gordon, MH, Lovegrove, JA & FLAVURS Study Group 2014, 'Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease-FLAVURS: a randomized controlled trial', American Journal of Clinical Nutrition, vol. 99, no. 3, pp. 479-489. https://doi.org/10.3945/ajcn.113.074237

Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease-FLAVURS: a randomized controlled trial. / Macready, Anna L; George, Trevor W; Chong, Mary F et al.
In: American Journal of Clinical Nutrition, Vol. 99, No. 3, 03.2014, p. 479-489.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Flavonoid-rich fruit and vegetables improve microvascular reactivity and inflammatory status in men at risk of cardiovascular disease-FLAVURS

T2 - a randomized controlled trial

AU - Macready, Anna L

AU - George, Trevor W

AU - Chong, Mary F

AU - Alimbetov, Dauren S

AU - Jin, Yannan

AU - Vidal, Alberto

AU - Spencer, Jeremy P E

AU - Kennedy, Orla B

AU - Tuohy, Kieran M

AU - Minihane, Anne-Marie

AU - Gordon, Michael H

AU - Lovegrove, Julie A

AU - FLAVURS Study Group

PY - 2014/3

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AB - Observed associations between increased fruit and vegetable (F&V) consumption, particularly those F&Vs that are rich in flavonoids, and vascular health improvements require confirmation in adequately powered randomized controlled trials.

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KW - Aged

KW - Anti-Inflammatory Agents, Non-Steroidal

KW - Biological Markers

KW - Cardiovascular Diseases

KW - Cohort Studies

KW - Cytokines

KW - England

KW - Female

KW - Flavonoids

KW - Fruit

KW - Humans

KW - Hypertension

KW - Male

KW - Microvessels

KW - Middle Aged

KW - Risk Factors

KW - Sex Characteristics

KW - Single-Blind Method

KW - Vascular Resistance

KW - Vascular Stiffness

KW - Vegetables

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DO - 10.3945/ajcn.113.074237

M3 - Article

C2 - 24452238

SN - 0002-9165

VL - 99

SP - 479

EP - 489

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

IS - 3

ER -