@article{baee84f810704ff791360f8b6cfee996,
title = "Fluorescence imaging of a potential diagnostic biomarker for breast cancer cells using a peptide-functionalized fluorogenic 2D material",
abstract = "Protein C receptor (PROCR) is a recently discovered transmembrane biomarker for several tissue stem cells and is highly expressed in triple-negative breast cancer (TNBC) patient-derived xenografts. Herein, to enrich the toolbox for the biochemical evaluation of PROCR, we have developed a peptide-functionalized fluorogenic 2D material based on the self-assembly between a fluorescent peptide probe and thin-layer molybdenum disulfide. The material developed was suitable for the sensitive detection of PROCR recombinant protein in buffer solution and the fluorescence imaging of TNBC cells that express high levels of PROCR.",
author = "Dou, {Wei Tao} and Liu, {Li Fang} and Jie Gao and Yi Zang and Chen, {Guo Rong} and Field, {Robert A.} and James, {Tony D.} and Jia Li and He, {Xiao Peng}",
note = "Funding Information: Prof. Yi Zeng is warmly thanked for her helpful discussion. This research was supported by the Natural Science Foundation of China (no. 21788102, 91853201, 21722801 and 21776078), the Shanghai Municipal Science and Technology Major Project (No. 2018SHZDZX03), the Shanghai Science and Technology Committee (No. 19410712600), and the National Postdoctoral Program for Innovative Talents (BX20190115). T. D. J. thanks the Royal Society for a Wolfson Research Merit Award. All cells were obtained from ATCC. Publisher Copyright: This journal is {\textcopyright} The Royal Society of Chemistry.",
year = "2019",
doi = "10.1039/c9cc06399d",
language = "English",
volume = "55",
pages = "13235--13238",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "88",
}
