Formal synthesis of (+)-lactacystin from l-serine

Philip C. Bulman Page, Ross L. Goodyear, Yohan Chan, Alexandra M.Z. Slawin, Steven M. Allin

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Abstract

A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

Original languageEnglish
Pages (from-to)30019-30032
Number of pages14
JournalRSC Advances
Volume9
Issue number51
DOIs
Publication statusPublished - 24 Sep 2019

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