Formal synthesis of (+)-lactacystin from l-serine

Philip C. Bulman Page; Ross L. Goodyear; Yohan Chan; Alexandra M.Z. Slawin; Steven M. Allin

doi:10.1039/c9ra07244f

Formal synthesis of (+)-lactacystin from l-serine

Philip C. Bulman Page, Ross L. Goodyear, Yohan Chan, Alexandra M.Z. Slawin, Steven M. Allin

Chemistry of Materials and Catalysis

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

22 Downloads (Pure)

Abstract

A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

Original language	English
Pages (from-to)	30019-30032
Number of pages	14
Journal	RSC Advances
Volume	9
Issue number	51
DOIs	https://doi.org/10.1039/c9ra07244f
Publication status	Published - 24 Sep 2019

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10.1039/c9ra07244fLicence: CC BY

Published_ManuscriptFinal published version, 1.18 MBLicence: CC BY

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title = "Formal synthesis of (+)-lactacystin from l-serine",

abstract = "A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.",

author = "{Bulman Page}, {Philip C.} and Goodyear, {Ross L.} and Yohan Chan and Slawin, {Alexandra M.Z.} and Allin, {Steven M.}",

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AU - Bulman Page, Philip C.

AU - Goodyear, Ross L.

AU - Chan, Yohan

AU - Slawin, Alexandra M.Z.

AU - Allin, Steven M.

PY - 2019/9/24

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AB - A formal, stereocontrolled synthesis of lactacystin has been completed from t-Bu-O-l-serine, providing the key intermediate 13, also useful for the generation of a range of C-9 analogues.

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DO - 10.1039/c9ra07244f

M3 - Article

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JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

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Formal synthesis of (+)-lactacystin from l-serine

Abstract

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