Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju; Jose M. C. Tubio; William Mifsud; Beiyuan Fu; Helen R. Davies; Manasa Ramakrishna; Yilong Li; Lucy Yates; Gunes Gundem; Patrick S. Tarpey; Sam Behjati; Elli Papaemmanuil; Sancha Martin; Anthony Fullam; Moritz Gerstung; Jyoti Nangalia; Anthony R. Green; Carlos Caldas; Åke Borg; Andrew Tutt; Ming Ta Michael Lee; Laura J. van't Veer; Benita K. T. Tan; Samuel Aparicio; Paul N. Span; John W. M. Martens; Stian Knappskog; Anne Vincent-Salomon; Anne-Lise Børresen-Dale; Jórunn Erla Eyfjörd; Adrienne M. Flanagan; Christopher Foster; David E. Neal; Colin Cooper; Rosalind Eeles; Sunil R. Lakhani; Christine Desmedt; Gilles Thomas; Andrea L. Richardson; Colin A. Purdie; Alastair M. Thompson; Ultan McDermott; Fengtang Yang; Serena Nik-Zainal; Peter J. Campbell; Michael R. Stratton

doi:10.1101/gr.190470.115

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju, Jose M. C. Tubio, William Mifsud, Beiyuan Fu, Helen R. Davies, Manasa Ramakrishna, Yilong Li, Lucy Yates, Gunes Gundem, Patrick S. Tarpey, Sam Behjati, Elli Papaemmanuil, Sancha Martin, Anthony Fullam, Moritz Gerstung, Jyoti Nangalia, Anthony R. Green, Carlos Caldas, Åke Borg, Andrew TuttMing Ta Michael Lee, Laura J. van't Veer, Benita K. T. Tan, Samuel Aparicio, Paul N. Span, John W. M. Martens, Stian Knappskog, Anne Vincent-Salomon, Anne-Lise Børresen-Dale, Jórunn Erla Eyfjörd, Adrienne M. Flanagan, Christopher Foster, David E. Neal, Colin Cooper, Rosalind Eeles, Sunil R. Lakhani, Christine Desmedt, Gilles Thomas, Andrea L. Richardson, Colin A. Purdie, Alastair M. Thompson, Ultan McDermott, Fengtang Yang, Serena Nik-Zainal, Peter J. Campbell, Michael R. Stratton

Research output: Contribution to journal › Article › peer-review

50 Citations (Scopus)

6 Downloads (Pure)

Original language	English
Pages (from-to)	814-824
Number of pages	11
Journal	Genome Research
Volume	25
Issue number	6
Early online date	11 May 2015
DOIs	https://doi.org/10.1101/gr.190470.115
Publication status	Published - Jun 2015

Access to Document

10.1101/gr.190470.115

Genome Res.-2015-Ju-814-24Final published version, 1.55 MB

Cite this

Ju, Y. S., Tubio, J. M. C., Mifsud, W., Fu, B., Davies, H. R., Ramakrishna, M., Li, Y., Yates, L., Gundem, G., Tarpey, P. S., Behjati, S., Papaemmanuil, E., Martin, S., Fullam, A., Gerstung, M., Nangalia, J., Green, A. R., Caldas, C., Borg, Å., ... Stratton, M. R. (2015). Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. Genome Research, 25(6), 814-824. https://doi.org/10.1101/gr.190470.115

Ju, Young Seok ; Tubio, Jose M. C. ; Mifsud, William ; Fu, Beiyuan ; Davies, Helen R. ; Ramakrishna, Manasa ; Li, Yilong ; Yates, Lucy ; Gundem, Gunes ; Tarpey, Patrick S. ; Behjati, Sam ; Papaemmanuil, Elli ; Martin, Sancha ; Fullam, Anthony ; Gerstung, Moritz ; Nangalia, Jyoti ; Green, Anthony R. ; Caldas, Carlos ; Borg, Åke ; Tutt, Andrew ; Lee, Ming Ta Michael ; van't Veer, Laura J. ; Tan, Benita K. T. ; Aparicio, Samuel ; Span, Paul N. ; Martens, John W. M. ; Knappskog, Stian ; Vincent-Salomon, Anne ; Børresen-Dale, Anne-Lise ; Eyfjörd, Jórunn Erla ; Flanagan, Adrienne M. ; Foster, Christopher ; Neal, David E. ; Cooper, Colin ; Eeles, Rosalind ; Lakhani, Sunil R. ; Desmedt, Christine ; Thomas, Gilles ; Richardson, Andrea L. ; Purdie, Colin A. ; Thompson, Alastair M. ; McDermott, Ultan ; Yang, Fengtang ; Nik-Zainal, Serena ; Campbell, Peter J. ; Stratton, Michael R. / Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. In: Genome Research. 2015 ; Vol. 25, No. 6. pp. 814-824.

@article{526f6b2e6ccd44f4a8c24628879cfc02,

title = "Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells",

author = "Ju, {Young Seok} and Tubio, {Jose M. C.} and William Mifsud and Beiyuan Fu and Davies, {Helen R.} and Manasa Ramakrishna and Yilong Li and Lucy Yates and Gunes Gundem and Tarpey, {Patrick S.} and Sam Behjati and Elli Papaemmanuil and Sancha Martin and Anthony Fullam and Moritz Gerstung and Jyoti Nangalia and Green, {Anthony R.} and Carlos Caldas and {\AA}ke Borg and Andrew Tutt and Lee, {Ming Ta Michael} and {van't Veer}, {Laura J.} and Tan, {Benita K. T.} and Samuel Aparicio and Span, {Paul N.} and Martens, {John W. M.} and Stian Knappskog and Anne Vincent-Salomon and Anne-Lise B{\o}rresen-Dale and Eyfj{\"o}rd, {J{\'o}runn Erla} and Flanagan, {Adrienne M.} and Christopher Foster and Neal, {David E.} and Colin Cooper and Rosalind Eeles and Lakhani, {Sunil R.} and Christine Desmedt and Gilles Thomas and Richardson, {Andrea L.} and Purdie, {Colin A.} and Thompson, {Alastair M.} and Ultan McDermott and Fengtang Yang and Serena Nik-Zainal and Campbell, {Peter J.} and Stratton, {Michael R.}",

year = "2015",

month = jun,

doi = "10.1101/gr.190470.115",

language = "English",

volume = "25",

pages = "814--824",

journal = "Genome Research",

issn = "1088-9051",

publisher = "Cold Spring Harbor Laboratory Press",

number = "6",

}

Ju, YS, Tubio, JMC, Mifsud, W, Fu, B, Davies, HR, Ramakrishna, M, Li, Y, Yates, L, Gundem, G, Tarpey, PS, Behjati, S, Papaemmanuil, E, Martin, S, Fullam, A, Gerstung, M, Nangalia, J, Green, AR, Caldas, C, Borg, Å, Tutt, A, Lee, MTM, van't Veer, LJ, Tan, BKT, Aparicio, S, Span, PN, Martens, JWM, Knappskog, S, Vincent-Salomon, A, Børresen-Dale, A-L, Eyfjörd, JE, Flanagan, AM, Foster, C, Neal, DE, Cooper, C, Eeles, R, Lakhani, SR, Desmedt, C, Thomas, G, Richardson, AL, Purdie, CA, Thompson, AM, McDermott, U, Yang, F, Nik-Zainal, S, Campbell, PJ & Stratton, MR 2015, 'Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells', Genome Research, vol. 25, no. 6, pp. 814-824. https://doi.org/10.1101/gr.190470.115

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. / Ju, Young Seok; Tubio, Jose M. C.; Mifsud, William; Fu, Beiyuan; Davies, Helen R.; Ramakrishna, Manasa; Li, Yilong; Yates, Lucy; Gundem, Gunes; Tarpey, Patrick S.; Behjati, Sam; Papaemmanuil, Elli; Martin, Sancha; Fullam, Anthony; Gerstung, Moritz; Nangalia, Jyoti; Green, Anthony R.; Caldas, Carlos; Borg, Åke; Tutt, Andrew; Lee, Ming Ta Michael; van't Veer, Laura J.; Tan, Benita K. T.; Aparicio, Samuel; Span, Paul N.; Martens, John W. M.; Knappskog, Stian; Vincent-Salomon, Anne; Børresen-Dale, Anne-Lise; Eyfjörd, Jórunn Erla; Flanagan, Adrienne M.; Foster, Christopher; Neal, David E.; Cooper, Colin; Eeles, Rosalind; Lakhani, Sunil R.; Desmedt, Christine; Thomas, Gilles; Richardson, Andrea L.; Purdie, Colin A.; Thompson, Alastair M.; McDermott, Ultan; Yang, Fengtang; Nik-Zainal, Serena; Campbell, Peter J.; Stratton, Michael R.

In: Genome Research, Vol. 25, No. 6, 06.2015, p. 814-824.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

AU - Ju, Young Seok

AU - Tubio, Jose M. C.

AU - Mifsud, William

AU - Fu, Beiyuan

AU - Davies, Helen R.

AU - Ramakrishna, Manasa

AU - Li, Yilong

AU - Yates, Lucy

AU - Gundem, Gunes

AU - Tarpey, Patrick S.

AU - Behjati, Sam

AU - Papaemmanuil, Elli

AU - Martin, Sancha

AU - Fullam, Anthony

AU - Gerstung, Moritz

AU - Nangalia, Jyoti

AU - Green, Anthony R.

AU - Caldas, Carlos

AU - Borg, Åke

AU - Tutt, Andrew

AU - Lee, Ming Ta Michael

AU - van't Veer, Laura J.

AU - Tan, Benita K. T.

AU - Aparicio, Samuel

AU - Span, Paul N.

AU - Martens, John W. M.

AU - Knappskog, Stian

AU - Vincent-Salomon, Anne

AU - Børresen-Dale, Anne-Lise

AU - Eyfjörd, Jórunn Erla

AU - Flanagan, Adrienne M.

AU - Foster, Christopher

AU - Neal, David E.

AU - Cooper, Colin

AU - Eeles, Rosalind

AU - Lakhani, Sunil R.

AU - Desmedt, Christine

AU - Thomas, Gilles

AU - Richardson, Andrea L.

AU - Purdie, Colin A.

AU - Thompson, Alastair M.

AU - McDermott, Ultan

AU - Yang, Fengtang

AU - Nik-Zainal, Serena

AU - Campbell, Peter J.

AU - Stratton, Michael R.

PY - 2015/6

Y1 - 2015/6

U2 - 10.1101/gr.190470.115

DO - 10.1101/gr.190470.115

M3 - Article

VL - 25

SP - 814

EP - 824

JO - Genome Research

JF - Genome Research

SN - 1088-9051

IS - 6

ER -