Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju; Jose M. C. Tubio; William Mifsud; Beiyuan Fu; Helen R. Davies; Manasa Ramakrishna; Yilong Li; Lucy Yates; Gunes Gundem; Patrick S. Tarpey; Sam Behjati; Elli Papaemmanuil; Sancha Martin; Anthony Fullam; Moritz Gerstung; ICGC Prostate Cancer Working Group; ICGC Bone Cancer Working Group; ICGC Breast Cancer Working Group; Jyoti Nangalia; Anthony R. Green; Carlos Caldas; Åke Borg; Andrew Tutt; Ming Ta Michael Lee; Laura J. van'T Veer; Benita K. T. Tan; Samuel Aparicio; Paul N. Span; John W. M. Martens; Stian Knappskog; Anne Vincent-Salomon; Anne-Lise Børresen-Dale; Jórunn Erla Eyfjörd; Ola Myklebost; Adrienne M. Flanagan; Christopher Foster; David E. Neal; Colin Cooper; Rosalind Eeles; G. Steven Bova; Sunil R. Lakhani; Christine Desmedt; Gilles Thomas; Andrea L. Richardson; Colin A. Purdie; Alastair M. Thompson; Ultan McDermott; Fengtang Yang; Serena Nik-Zainal; Peter J. Campbell; Michael R. Stratton

doi:10.1101/gr.190470.115

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

Young Seok Ju, Jose M. C. Tubio, William Mifsud, Beiyuan Fu, Helen R. Davies, Manasa Ramakrishna, Yilong Li, Lucy Yates, Gunes Gundem, Patrick S. Tarpey, Sam Behjati, Elli Papaemmanuil, Sancha Martin, Anthony Fullam, Moritz Gerstung, ICGC Prostate Cancer Working Group, ICGC Bone Cancer Working Group, ICGC Breast Cancer Working Group, Jyoti Nangalia, Anthony R. GreenCarlos Caldas, Åke Borg, Andrew Tutt, Ming Ta Michael Lee, Laura J. van'T Veer, Benita K. T. Tan, Samuel Aparicio, Paul N. Span, John W. M. Martens, Stian Knappskog, Anne Vincent-Salomon, Anne-Lise Børresen-Dale, Jórunn Erla Eyfjörd, Ola Myklebost, Adrienne M. Flanagan, Christopher Foster, David E. Neal, Colin Cooper, Rosalind Eeles, G. Steven Bova, Sunil R. Lakhani, Christine Desmedt, Gilles Thomas, Andrea L. Richardson, Colin A. Purdie, Alastair M. Thompson, Ultan McDermott, Fengtang Yang, Serena Nik-Zainal, Peter J. Campbell, Michael R. Stratton

Research output: Contribution to journal › Article › peer-review

48 Citations (SciVal)

6 Downloads (Pure)

Original language	English
Pages (from-to)	814-824
Number of pages	11
Journal	Genome Research
Volume	25
Issue number	6
Early online date	11 May 2015
DOIs	https://doi.org/10.1101/gr.190470.115 https://doi.org/10.1101/gr.206557.116
Publication status	Published - Jun 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

Genome Res.-2015-Ju-814-24Final published version, 1.55 MB

Cite this

Ju, Y. S., Tubio, J. M. C., Mifsud, W., Fu, B., Davies, H. R., Ramakrishna, M., Li, Y., Yates, L., Gundem, G., Tarpey, P. S., Behjati, S., Papaemmanuil, E., Martin, S., Fullam, A., Gerstung, M., ICGC Prostate Cancer Working Group, ICGC Bone Cancer Working Group, ICGC Breast Cancer Working Group, Nangalia, J., ... Stratton, M. R. (2015). Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. Genome Research, 25(6), 814-824. https://doi.org/10.1101/gr.190470.115, https://doi.org/10.1101/gr.206557.116

Ju, Young Seok ; Tubio, Jose M. C. ; Mifsud, William ; Fu, Beiyuan ; Davies, Helen R. ; Ramakrishna, Manasa ; Li, Yilong ; Yates, Lucy ; Gundem, Gunes ; Tarpey, Patrick S. ; Behjati, Sam ; Papaemmanuil, Elli ; Martin, Sancha ; Fullam, Anthony ; Gerstung, Moritz ; ICGC Prostate Cancer Working Group ; ICGC Bone Cancer Working Group ; ICGC Breast Cancer Working Group ; Nangalia, Jyoti ; Green, Anthony R. ; Caldas, Carlos ; Borg, Åke ; Tutt, Andrew ; Lee, Ming Ta Michael ; van'T Veer, Laura J. ; Tan, Benita K. T. ; Aparicio, Samuel ; Span, Paul N. ; Martens, John W. M. ; Knappskog, Stian ; Vincent-Salomon, Anne ; Børresen-Dale, Anne-Lise ; Eyfjörd, Jórunn Erla ; Myklebost, Ola ; Flanagan, Adrienne M. ; Foster, Christopher ; Neal, David E. ; Cooper, Colin ; Eeles, Rosalind ; Bova, G. Steven ; Lakhani, Sunil R. ; Desmedt, Christine ; Thomas, Gilles ; Richardson, Andrea L. ; Purdie, Colin A. ; Thompson, Alastair M. ; McDermott, Ultan ; Yang, Fengtang ; Nik-Zainal, Serena ; Campbell, Peter J. ; Stratton, Michael R. / Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. In: Genome Research. 2015 ; Vol. 25, No. 6. pp. 814-824.

@article{526f6b2e6ccd44f4a8c24628879cfc02,

title = "Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells",

author = "Ju, {Young Seok} and Tubio, {Jose M. C.} and William Mifsud and Beiyuan Fu and Davies, {Helen R.} and Manasa Ramakrishna and Yilong Li and Lucy Yates and Gunes Gundem and Tarpey, {Patrick S.} and Sam Behjati and Elli Papaemmanuil and Sancha Martin and Anthony Fullam and Moritz Gerstung and {ICGC Prostate Cancer Working Group} and {ICGC Bone Cancer Working Group} and {ICGC Breast Cancer Working Group} and Jyoti Nangalia and Green, {Anthony R.} and Carlos Caldas and {\AA}ke Borg and Andrew Tutt and Lee, {Ming Ta Michael} and {van'T Veer}, {Laura J.} and Tan, {Benita K. T.} and Samuel Aparicio and Span, {Paul N.} and Martens, {John W. M.} and Stian Knappskog and Anne Vincent-Salomon and Anne-Lise B{\o}rresen-Dale and Eyfj{\"o}rd, {J{\'o}runn Erla} and Ola Myklebost and Flanagan, {Adrienne M.} and Christopher Foster and Neal, {David E.} and Colin Cooper and Rosalind Eeles and Bova, {G. Steven} and Lakhani, {Sunil R.} and Christine Desmedt and Gilles Thomas and Richardson, {Andrea L.} and Purdie, {Colin A.} and Thompson, {Alastair M.} and Ultan McDermott and Fengtang Yang and Serena Nik-Zainal and Campbell, {Peter J.} and Stratton, {Michael R.}",

year = "2015",

month = jun,

doi = "10.1101/gr.190470.115",

language = "English",

volume = "25",

pages = "814--824",

journal = "Genome Research",

issn = "1088-9051",

publisher = "Cold Spring Harbor Laboratory Press",

number = "6",

}

Ju, YS, Tubio, JMC, Mifsud, W, Fu, B, Davies, HR, Ramakrishna, M, Li, Y, Yates, L, Gundem, G, Tarpey, PS, Behjati, S, Papaemmanuil, E, Martin, S, Fullam, A, Gerstung, M, ICGC Prostate Cancer Working Group, ICGC Bone Cancer Working Group, ICGC Breast Cancer Working Group, Nangalia, J, Green, AR, Caldas, C, Borg, Å, Tutt, A, Lee, MTM, van'T Veer, LJ, Tan, BKT, Aparicio, S, Span, PN, Martens, JWM, Knappskog, S, Vincent-Salomon, A, Børresen-Dale, A-L, Eyfjörd, JE, Myklebost, O, Flanagan, AM, Foster, C, Neal, DE, Cooper, C, Eeles, R, Bova, GS, Lakhani, SR, Desmedt, C, Thomas, G, Richardson, AL, Purdie, CA, Thompson, AM, McDermott, U, Yang, F, Nik-Zainal, S, Campbell, PJ & Stratton, MR 2015, 'Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells', Genome Research, vol. 25, no. 6, pp. 814-824. https://doi.org/10.1101/gr.190470.115, https://doi.org/10.1101/gr.206557.116

Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. / Ju, Young Seok; Tubio, Jose M. C.; Mifsud, William; Fu, Beiyuan; Davies, Helen R.; Ramakrishna, Manasa; Li, Yilong; Yates, Lucy; Gundem, Gunes; Tarpey, Patrick S.; Behjati, Sam; Papaemmanuil, Elli; Martin, Sancha; Fullam, Anthony; Gerstung, Moritz; ICGC Prostate Cancer Working Group; ICGC Bone Cancer Working Group; ICGC Breast Cancer Working Group; Nangalia, Jyoti; Green, Anthony R.; Caldas, Carlos; Borg, Åke; Tutt, Andrew; Lee, Ming Ta Michael; van'T Veer, Laura J.; Tan, Benita K. T.; Aparicio, Samuel; Span, Paul N.; Martens, John W. M.; Knappskog, Stian; Vincent-Salomon, Anne; Børresen-Dale, Anne-Lise; Eyfjörd, Jórunn Erla; Myklebost, Ola; Flanagan, Adrienne M.; Foster, Christopher; Neal, David E.; Cooper, Colin; Eeles, Rosalind; Bova, G. Steven; Lakhani, Sunil R.; Desmedt, Christine; Thomas, Gilles; Richardson, Andrea L.; Purdie, Colin A.; Thompson, Alastair M.; McDermott, Ultan; Yang, Fengtang; Nik-Zainal, Serena; Campbell, Peter J.; Stratton, Michael R.

In: Genome Research, Vol. 25, No. 6, 06.2015, p. 814-824.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

AU - Ju, Young Seok

AU - Tubio, Jose M. C.

AU - Mifsud, William

AU - Fu, Beiyuan

AU - Davies, Helen R.

AU - Ramakrishna, Manasa

AU - Li, Yilong

AU - Yates, Lucy

AU - Gundem, Gunes

AU - Tarpey, Patrick S.

AU - Behjati, Sam

AU - Papaemmanuil, Elli

AU - Martin, Sancha

AU - Fullam, Anthony

AU - Gerstung, Moritz

AU - ICGC Prostate Cancer Working Group

AU - ICGC Bone Cancer Working Group

AU - ICGC Breast Cancer Working Group

AU - Nangalia, Jyoti

AU - Green, Anthony R.

AU - Caldas, Carlos

AU - Borg, Åke

AU - Tutt, Andrew

AU - Lee, Ming Ta Michael

AU - van'T Veer, Laura J.

AU - Tan, Benita K. T.

AU - Aparicio, Samuel

AU - Span, Paul N.

AU - Martens, John W. M.

AU - Knappskog, Stian

AU - Vincent-Salomon, Anne

AU - Børresen-Dale, Anne-Lise

AU - Eyfjörd, Jórunn Erla

AU - Myklebost, Ola

AU - Flanagan, Adrienne M.

AU - Foster, Christopher

AU - Neal, David E.

AU - Cooper, Colin

AU - Eeles, Rosalind

AU - Bova, G. Steven

AU - Lakhani, Sunil R.

AU - Desmedt, Christine

AU - Thomas, Gilles

AU - Richardson, Andrea L.

AU - Purdie, Colin A.

AU - Thompson, Alastair M.

AU - McDermott, Ultan

AU - Yang, Fengtang

AU - Nik-Zainal, Serena

AU - Campbell, Peter J.

AU - Stratton, Michael R.

PY - 2015/6

Y1 - 2015/6

U2 - 10.1101/gr.190470.115

DO - 10.1101/gr.190470.115

M3 - Article

VL - 25

SP - 814

EP - 824

JO - Genome Research

JF - Genome Research

SN - 1088-9051

IS - 6

ER -