Gene expression of transporters and phase I/II metabolic enzymes in murine small intestine during fasting

Heleen M van den Bosch, Meike Bünger, Philip J de Groot, Jolanda van der Meijde, Guido J E J Hooiveld, Michael Müller

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

Fasting has dramatic effects on small intestinal transport function. However, little is known on expression of intestinal transport and phase I/II metabolism genes during fasting and the role the fatty acid-activated transcription factor PPARalpha may play herein. We therefore investigated the effects of fasting on expression of these genes using Affymetrix GeneChip MOE430A arrays and quantitative RT-PCR.
Original languageEnglish
Article number267
JournalBMC Genomics
Volume8
DOIs
Publication statusPublished - 7 Aug 2007

Keywords

  • ATP-Binding Cassette Transporters
  • Animals
  • Fasting
  • Gene Expression Profiling
  • Gene Expression Regulation
  • Small Intestine
  • Metabolic Networks and Pathways
  • Mice
  • Oligonucleotide Array Sequence Analysis
  • Organic Anion Transporters
  • PPAR alpha
  • Time Factors

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