Genetic variation in myosin IXB is associated with ulcerative colitis

Adriaan A van Bodegraven; Christine R Curley; Karen A Hunt; Alienke J Monsuur; Ronald K Linskens; Clive M Onnie; J Bart A Crusius; Vito Annese; Anna Latiano; Mark S Silverberg; Alain Bitton; Sheila A Fisher; A Hilary Steinhart; Alastair Forbes; Jeremy Sanderson; Natalie J Prescott; David P Strachan; Raymond J Playford; Christopher G Mathew; Cisca Wijmenga; Mark J Daly; John D Rioux; David A van Heel

doi:10.1053/j.gastro.2006.09.011

Genetic variation in myosin IXB is associated with ulcerative colitis

Adriaan A van Bodegraven
, Christine R Curley
, Karen A Hunt
, Alienke J Monsuur
, Ronald K Linskens
, Clive M Onnie
, J Bart A Crusius
, Vito Annese
, Anna Latiano
, Mark S Silverberg
, Alain Bitton
, Sheila A Fisher
, A Hilary Steinhart
, Alastair Forbes
, Jeremy Sanderson
, Natalie J Prescott
, David P Strachan
, Raymond J Playford
, Christopher G Mathew
, Cisca Wijmenga

Mark J Daly, John D Rioux, David A van Heel

Research output: Contribution to journal › Article › peer-review

99 Citations (Scopus)

Abstract

Common germline genetic variation in the 3' region of myosin IXB (MYO9B) has been associated recently with susceptibility to celiac disease, with a hypothesis that MYO9B variants might influence intestinal permeability. These findings suggested the current study investigating a possible further role for MYO9B variation in inflammatory bowel disease.

Original language	English
Pages (from-to)	1768-74
Number of pages	7
Journal	Gastroenterology
Volume	131
Issue number	6
DOIs	https://doi.org/10.1053/j.gastro.2006.09.011
Publication status	Published - Dec 2006

Keywords

Adolescent
Adult
Aged
Aged, 80 and over
Case-Control Studies
Child
Cohort Studies
Colitis, Ulcerative
European Continental Ancestry Group
Female
Genetic Predisposition to Disease
Genetic Variation
Genotype
Humans
Male
Middle Aged
Myosins
Polymorphism, Single Nucleotide

Access to Document

10.1053/j.gastro.2006.09.011

Cite this

van Bodegraven, A. A., Curley, C. R., Hunt, K. A., Monsuur, A. J., Linskens, R. K., Onnie, C. M., Crusius, J. B. A., Annese, V., Latiano, A., Silverberg, M. S., Bitton, A., Fisher, S. A., Steinhart, A. H., Forbes, A., Sanderson, J., Prescott, N. J., Strachan, D. P., Playford, R. J., Mathew, C. G., ... van Heel, D. A. (2006). Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology, 131(6), 1768-74. https://doi.org/10.1053/j.gastro.2006.09.011

@article{23319378c6ee4f65acacb2361ceff4a3,

title = "Genetic variation in myosin IXB is associated with ulcerative colitis",

abstract = "Common germline genetic variation in the 3' region of myosin IXB (MYO9B) has been associated recently with susceptibility to celiac disease, with a hypothesis that MYO9B variants might influence intestinal permeability. These findings suggested the current study investigating a possible further role for MYO9B variation in inflammatory bowel disease.",

keywords = "Adolescent, Adult, Aged, Aged, 80 and over, Case-Control Studies, Child, Cohort Studies, Colitis, Ulcerative, European Continental Ancestry Group, Female, Genetic Predisposition to Disease, Genetic Variation, Genotype, Humans, Male, Middle Aged, Myosins, Polymorphism, Single Nucleotide",

author = "\{van Bodegraven\}, \{Adriaan A\} and Curley, \{Christine R\} and Hunt, \{Karen A\} and Monsuur, \{Alienke J\} and Linskens, \{Ronald K\} and Onnie, \{Clive M\} and Crusius, \{J Bart A\} and Vito Annese and Anna Latiano and Silverberg, \{Mark S\} and Alain Bitton and Fisher, \{Sheila A\} and Steinhart, \{A Hilary\} and Alastair Forbes and Jeremy Sanderson and Prescott, \{Natalie J\} and Strachan, \{David P\} and Playford, \{Raymond J\} and Mathew, \{Christopher G\} and Cisca Wijmenga and Daly, \{Mark J\} and Rioux, \{John D\} and \{van Heel\}, \{David A\}",

year = "2006",

month = dec,

doi = "10.1053/j.gastro.2006.09.011",

language = "English",

volume = "131",

pages = "1768--74",

journal = "Gastroenterology",

issn = "0016-5085",

publisher = "Elsevier",

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}

van Bodegraven, AA, Curley, CR, Hunt, KA, Monsuur, AJ, Linskens, RK, Onnie, CM, Crusius, JBA, Annese, V, Latiano, A, Silverberg, MS, Bitton, A, Fisher, SA, Steinhart, AH, Forbes, A, Sanderson, J, Prescott, NJ, Strachan, DP, Playford, RJ, Mathew, CG, Wijmenga, C, Daly, MJ, Rioux, JD & van Heel, DA 2006, 'Genetic variation in myosin IXB is associated with ulcerative colitis', Gastroenterology, vol. 131, no. 6, pp. 1768-74. https://doi.org/10.1053/j.gastro.2006.09.011

TY - JOUR

T1 - Genetic variation in myosin IXB is associated with ulcerative colitis

AU - van Bodegraven, Adriaan A

AU - Curley, Christine R

AU - Hunt, Karen A

AU - Monsuur, Alienke J

AU - Linskens, Ronald K

AU - Onnie, Clive M

AU - Crusius, J Bart A

AU - Annese, Vito

AU - Latiano, Anna

AU - Silverberg, Mark S

AU - Bitton, Alain

AU - Fisher, Sheila A

AU - Steinhart, A Hilary

AU - Forbes, Alastair

AU - Sanderson, Jeremy

AU - Prescott, Natalie J

AU - Strachan, David P

AU - Playford, Raymond J

AU - Mathew, Christopher G

AU - Wijmenga, Cisca

AU - Daly, Mark J

AU - Rioux, John D

AU - van Heel, David A

PY - 2006/12

Y1 - 2006/12

N2 - Common germline genetic variation in the 3' region of myosin IXB (MYO9B) has been associated recently with susceptibility to celiac disease, with a hypothesis that MYO9B variants might influence intestinal permeability. These findings suggested the current study investigating a possible further role for MYO9B variation in inflammatory bowel disease.

AB - Common germline genetic variation in the 3' region of myosin IXB (MYO9B) has been associated recently with susceptibility to celiac disease, with a hypothesis that MYO9B variants might influence intestinal permeability. These findings suggested the current study investigating a possible further role for MYO9B variation in inflammatory bowel disease.

KW - Adolescent

KW - Adult

KW - Aged

KW - Aged, 80 and over

KW - Case-Control Studies

KW - Child

KW - Cohort Studies

KW - Colitis, Ulcerative

KW - European Continental Ancestry Group

KW - Female

KW - Genetic Predisposition to Disease

KW - Genetic Variation

KW - Genotype

KW - Humans

KW - Male

KW - Middle Aged

KW - Myosins

KW - Polymorphism, Single Nucleotide

U2 - 10.1053/j.gastro.2006.09.011

DO - 10.1053/j.gastro.2006.09.011

M3 - Article

C2 - 17087940

SN - 0016-5085

VL - 131

SP - 1768

EP - 1774

JO - Gastroenterology

JF - Gastroenterology

IS - 6

ER -