Getting the payload in place - Unravelling the complexities of making a bacterial microcompartment

Michael D. Paxhia, Mingzhi Liang, Martin J. Warren

Research output: Contribution to journalComment/debatepeer-review


Bacterial microcompartments (BMCs) are complex macromolecular assemblies composed of any outer protein shell that encases a specific metabolic pathway cargo. Recent research is now starting to unravel some of the processes that are involved in directing the enzyme cargo to the inside of the BMC. In particular, an article in this issue of J Bacteriol by N. W. Kennedy, C. E. Mills, C. H. Abrahamson, A. Archer, et al. (J Bacteriol 204:e00576-21, 2022, highlights the role played by the shell protein PduB in coordinating this internalization process.

Original languageEnglish
Article numbere0012722
JournalJournal of Bacteriology
Issue number9
Early online date24 Aug 2022
Publication statusPublished - 20 Sep 2022


  • bacterial microcompartment
  • cargo
  • enzyme
  • pathway

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