Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

Jayshree Ashree; Qi Wang; Yimin Chao

doi:10.1007/s11705-019-1863-7

Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

Jayshree Ashree, Qi Wang, Yimin Chao

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Abstract

Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.

Original language	English
Pages (from-to)	365–377
Number of pages	13
Journal	Frontiers of Chemical Science and Engineering
Volume	14
Issue number	3
Early online date	27 Sept 2019
DOIs	https://doi.org/10.1007/s11705-019-1863-7
Publication status	Published - Jun 2020

Keywords

bioimaging
cancer diagnosis and treatment
carbohydrate
glyco-functionalised QD
leptin

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s11705-019-1863-7Licence: CC BY

Front._Chem._Sci._Eng._Draft_2019-AugustAccepted author manuscript, 927 KBLicence: CC BY
Published_ManuscriptFinal published version, 2.37 MBLicence: CC BY

http://link.springer.com/10.1007/s11705-019-1863-7Licence: CC BY

Cite this

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abstract = "Despite all major breakthroughs in recent years of research, we are still unsuccessful to effectively diagnose and treat cancer that has express and metastasizes. Thus, the development of a novel approach for cancer detection and treatment is crucial. Recent progress in Glyconanotechnology has allowed the use of glycans and lectins as bio-functional molecules for many biological and biomedical applications. With the known advantages of quantum dots (QDs) and versatility of carbohydrates and lectins, Glyco-functionalised QD is a new prospect in constructing biomedical imaging platform for cancer behaviour study as well as treatment. In this review, we aim to describe the current utilisation of Glyco-functionalised QDs as well as their future prospective to interpret and confront cancer.",

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Glyco-functionalised quantum dots and their progress in cancer diagnosis and treatment

Abstract

Keywords

UN SDGs

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Yimin Chao

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